Left ventricular hypertrophy does not prevent heart failure in experimental hypertension.

Background: Left ventricular hypertrophy (LVH) secondary to hypertension has been accepted to prevent heart failure (HF) while paradoxically increasing cardiovascular morbi-mortality.

Objectives: To evaluate whether antihypertensive treatment inhibits LVH, restores beta-adrenergic response and affects myocardial oxidative metabolism.

Methods: Ninety spontaneously hypertensive rats (SHR) were distributed into groups and treated (mg/kg, p.

Cardiorenal Involvement in Metabolic Syndrome Induced by Cola Drinking in Rats: Proinflammatory Cytokines and Impaired Antioxidative Protection.

We report experimental evidence confirming renal histopathology, proinflammatory mediators, and oxidative metabolism induced by cola drinking. Male Wistar rats drank ad libitum regular cola (C, n = 12) or tap water (W, n = 12). Measures.

Chronic cola drinking induces metabolic and cardiac alterations in rats.

Aim: To investigate the effects of chronic drinking of cola beverages on metabolic and echocardiographic parameters in rats.

Methods: Forty-eight male Wistar rats were divided in 3 groups and allowed to drink regular cola (C), diet cola (L), or tap water (W) ad libitum during 6 mo. After this period, 50% of the animals in each group were euthanized.