Nigerian propolis: chemical composition, antioxidant activity and α-amylase and α-glucosidase inhibition.

Propolis is an attractive natural ingredient to design health products due to its pharmacological effects. Our chemical investigation of a polar extract of Nigerian propolis (NP) led the isolation and identification of five isoflavonoids (, ), one diarylpropane () and one prenylated flavanone () by the combination of chromatographic and spectroscopic techniques. Compounds , and were found to be the main markers in NP (8.

Analgesic and Antioxidant Activities of Stem Bark Extract and Fractions of Petersianthus macrocarpus.

Background: Petersianthus macrocarpus (Lecythidaceae) is widely used in the folk medicine in Nigeria to relieve pain and fever associated with malaria. This study evaluated the analgesic and antioxidant activities of the methanol extract and fractions of the stem bark of the plant.

Materials And Methods: The analgesic activity was determined in mice using hotplate and acetic acid-induced writhing models.