Publications by authors named "Herb Archer"
Article Synopsis
- - The study aimed to determine the impact of colchicine and high-intensity rosuvastatin on the progression of COVID-19 in hospitalized patients, compared to standard care alone.
- - Conducted as a randomized controlled trial across four centers within the Yale New Haven Health System, it involved 250 non-critically ill hospitalized COVID-19 patients, with a follow-up period of 30 days.
- - The trial was halted early for futility, as there was no notable difference in severe disease progression or thromboembolic events between the treatment group and the control group.
Background: Despite improvement in the standard of care (SOC) for hospitalized COVID-19 patients, rates of morbidity and mortality remain high. There continues to be a need for easily available and cost-effective treatments. Colchicine and rosuvastatin are both safe and well-studied medications with anti-inflammatory and other pleiotropic effects that may provide additional benefits to hospitalized COVID-19 patients.
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