Application of roc-analysis to assess the quality of predicting the risk of chronic rhinosinusitis recurrence.

Objective: Aim: To propose a new, original approach to assessing the quality of a multivariate regression model for predicting the risk of recurrence in patients with chronic rhinosinusitis based on ROC analysis with the construction of appropriate curves, estimating the area under them, as well as calculating the sensitivity, accuracy, specificity, and predictive value of a positive and negative classification results, the likelihood ratio of positive and negative patient detection results.

Patients And Methods: Materials and Methods: 204 patients aged with a diagnosis of chronic rhinosinusitis were examined.

Results: Results: To build a multivariate regression model 14 probable factors of chronic rhinosinusitis occurrence were selected to determine the diagnostic value of the proposed model we calculate the sensitivity (Se), specificity (Sp), positive predictive value (PPV), negative predictive value (NPV), the likelihood ratio of a positive test (LR+), the likelihood ratio of a negative test (LR-) and prediction accuracy % of the proposed mathematical model.

MULTIFACTOR REGRESSION MODEL FOR PREDICTION OF CHRONIC RHINOSINUSITIS RECURRENCE.

Objective: The aim: To propose an approach to forecasting the risk of chronic rhinosinusitis recurrence based on multivariate regression analysis for effective diagnosis and carrying out treatment and preventive measures.

Patients And Methods: Materials and methods: 104 patients aged 18 to 80, including 58 women and 46 men, diagnosed with chronic rhinosinusitis were examined.

Results: Results: To build a multifactorial regression model for predicting the recurrence of chronic rhinosinusitis, probable factors of the occurrence of the disease were selected.

[PECULIARITIES OF STRUCTURAL CHANGES IN RAT LUNGS IN APPLICATION OF DIFFERENT METHODS OF REHYDRATION AFTER GENERAL DEHYDRATION].

Dehydration of the organism leads to the disturbances in homeostasis and structural changes in the lungs. Inadequate rehydration can also lead to the undesirable consequences. Experiments were carried out on rats, which modeled general dehydration and its correction: with metered potable water consumption, with water consumption without restrictions and correction by using a physiological solution.