ULTRASTRUCTURAL FEATURES OF THE REARRANGEMENT OF THE CELLS OF THE HEMATOTESTICULAR BARRIER AND THE SPERMATOGENIC EPITHELIUM OF THE RATS TESTICLES DURING THE SUDDEN WITHDRAWAL OF PREDNISOLONE AFTER ITS LONG-TERM INTRODUCTION IN HIGH DOSES.

With long-term use of hormonal drugs, according to the principle of "negative feedback", the production of own hormones by the endocrine glands is inhibited. With sudden withdrawal, in particular, of glucocorticoids, there are processes that threaten the development of secondary adrenal insufficiency. The purpose of the study: to establish the peculiarities of the reconstruction of the cellular elements of the testicles of white rats after the withdrawal of high doses of prednisolone.

ULTRASTRUCTURAL FEATURES OF THE REARRANGEMENT OF CELLS OF THE HEMATOTESTICULAR BARRIER AND SPERMATOGENIC EPITHELIUM OF THE RATS TESTICLES AFTER INTRODUCTION OF HIGH DOSES OF PREDNISOLONE.

A feature of recent decades is the gradual increase in the level of male infertility, one of the important causes of which, of course, is endocrine dysfunction of various origins. Therefore, the aim of the study was to establish the features of the rearrangement of the testicle's cellular elements of white rats with the introduction of high doses of prednisolone. An ultrastructural study was carried out on 42 male rats.

CHARACTER AND SPECIFICS OF THE STRUCTURAL ALTERATION OF THE PARENCHYMA AND BLOODSTREAM OF THE TESTES OF WHITE RATS WITH PROLONGED ADMINISTRATION OF HIGH DOSES OF PREDNISOLONE.

Objective: The aim: To investigate the nature of morphofunctional changes in the parenchyma and bloodstream of the testes of white rats with prolonged administration of high doses of prednisolone.

Patients And Methods: Material and methods: The experiments were performed on rats fed daily for 1, 3, 7, 14 and 28 days. prednisolone was administered intramuscularly at a rate of 0.

[PECULIARITIES OF STRUCTURAL CHANGES IN RAT LUNGS IN APPLICATION OF DIFFERENT METHODS OF REHYDRATION AFTER GENERAL DEHYDRATION].

Dehydration of the organism leads to the disturbances in homeostasis and structural changes in the lungs. Inadequate rehydration can also lead to the undesirable consequences. Experiments were carried out on rats, which modeled general dehydration and its correction: with metered potable water consumption, with water consumption without restrictions and correction by using a physiological solution.

[A pathogenetic validation of a method for correcting portal hypertension].

The correction method of portal hypertension, basing on the blood circulation flow reduction in the main abdominal cavity arterial vessels, was elaborated in experiments on dogs. The functional and morphological changes in vascular bed and the abdominal cavity organs after the portal hypertension modelling and its surgical correction were studied up.

[A method for the internal drainage of the bile ducts].

The choledochoduodenostomy conduction method with the functionally active valve formation was proposed for the duodenocholedochal reflux via the anastomosis prophylaxis.