Renewable Syngas Generation via Low-Temperature Electrolysis: Opportunities and Challenges.

The production of syngas (i.e., a mixture of CO and H) via the electrochemical reduction of CO and water can contribute to the green transition of various industrial sectors.

VAPEX: an interactive web server for the deep exploration of natural virus and phage genomes.

Motivation: Studying the genetic makeup of viruses and phages through genome analysis is crucial for comprehending their function in causing diseases, progressing medicine, tracing their evolutionary history, monitoring the environment, and creating innovative biotechnologies. However, accessing the necessary data can be challenging due to a lack of dedicated comparative genomic tools and viral and phage databases, which are often outdated. Moreover, many wet bench experimentalists may not have the computational proficiency required to manipulate large amounts of genomic data.

BAGET 2.0: an updated web tool for the effortless retrieval of prokaryotic gene context and sequence.

Motivation: The retrieval of a single gene sequence and context from completely sequenced bacterial and archaeal genomes constitutes an intimidating task for the wet bench biologist. Existing web-based genome browsers are either too complex for routine use or only provide a subset of the available prokaryotic genomes.

Results: We have developed BAGET 2.

Noise Induces the Population-Level Entrainment of Incoherent, Uncoupled Intracellular Oscillators.

Intracellular oscillators entrain to periodic signals by adjusting their phase and frequency. However, the low copy numbers of key molecular players make the dynamics of these oscillators intrinsically noisy, disrupting their oscillatory activity and entrainment response. Here, we use a combination of computational methods and experimental observations to reveal a functional distinction between the entrainment of individual oscillators (e.

Adaptive hybrid simulations for multiscale stochastic reaction networks.

The probability distribution describing the state of a Stochastic Reaction Network (SRN) evolves according to the Chemical Master Equation (CME). It is common to estimate its solution using Monte Carlo methods such as the Stochastic Simulation Algorithm (SSA). In many cases, these simulations can take an impractical amount of computational time.

[Vitamin D supply of patients with hip fracture].

Introduction: Vitamin D deficiency is an important risk factor for fractures. However, there are few data available only on the relationship between serum 25-hydroxyvitamin D levels and recovery after surgery for hip fracture.

Aim: The authors investigate the vitamin D supply of patients with hip fractures.

[Follow-up our patients with proximal humeral fractures between 2000 and 2005].

Authors introduced a new method in 2000 for the operative treatment of proximal end of the humerus. Because of the anatomical properties of the shoulder, great emphasis is placed on the protection of the soft tissues of the joint, the minimal invasive operative technique. On the other hand, the osteoporosis, which presents itself in the old age, makes the osteosynthesis more difficult; the proportion of complication is high in spite of the most careful treatment.

PALMA: mRNA to genome alignments using large margin algorithms.

Motivation: Despite many years of research on how to properly align sequences in the presence of sequencing errors, alternative splicing and micro-exons, the correct alignment of mRNA sequences to genomic DNA is still a challenging task.

Results: We present a novel approach based on large margin learning that combines accurate splice site predictions with common sequence alignment techniques. By solving a convex optimization problem, our algorithm-called PALMA-tunes the parameters of the model such that true alignments score higher than other alignments.

Socio-economic impact of chronic venous insufficiency. An underestimated public health problem.

Background: Disease of the venous system is an underestimated public health problem affecting all Western industrialised countries. The prevalence of venous disease of the lower limb in the adult population is estimated at 40-50% for men and 50-55% for women, whereas visible varicose veins and chronic venous insufficiency are, respectively, present in 10-15% and 2-7% of the male population and 20-25% and 3-7% of the female population. In France the costs of venous disease represented 2.

Spinal cord stimulation in Belgium: a nation-wide survey on the incidence, indications and therapeutic efficacy by the health insurer.

The present report describes a nation-wide survey on the incidence, the indications and the efficacy of spinal cord stimulation (SCS), as assessed by the Belgian health authorities. The direct motive for this survey was the rapidly growing expenditures resulting from the increasing use of SCS. Between 1983 and 1992, nearly 700 SCS devices were implanted for a population of less than 10 million inhabitants.

Pharmacoeconomics of immunisation: a review.

The effects of immunisation programmes that have existed for several decades in developed countries are demonstrated by the decrease and even eradication of smallpox, poliomyelitis, measles, mumps and hepatitis B. Cost, health policy and spontaneous evolution in the incidence of communicable diseases have a decisive influence on the use of a vaccine. Investment in vaccination policy has to be encouraged to maintain this progress made in the control of infectious diseases and to meet new challenges.

Evidence of functional cellular immune impairment in an adult Belgian with visceral leishmaniasis acquired in Spain.

An adult Belgian patient with visceral leishmaniasis acquired while on holiday in Spain is described. This patient's cellular immunity was assessed by skin testing using six different antigens and was normal just before leaving for Spain. During the leishmaniasis, skin tests with the same antigens showed complete anergy.