Synopsis of recent research by authors named "Hepeng Xu"
- Hepeng Xu's recent research primarily focuses on the mechanisms of chronic kidney disease (CKD) and its complications during pregnancy, particularly investigating the efficacy of eplerenone in modulating the SGK1/TGF-β pathway to alleviate renal fibrosis in CKD pregnancy models.
- Additionally, Xu has explored the emerging field of ferroptosis, highlighting its role in various autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus, thus linking cellular death mechanisms to immune dysregulation.
- Further investigations involve traditional Chinese medicine, specifically the Yiqi Huoxue Tongluo recipe, which appears to improve renal mitochondrial function in CKD models by regulating NR4A1, showcasing an integration of alternative therapies in modern biomedical research.