Publications by authors named "Heon-Sik Lee"
Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and L-carnitine: implications in cardiovascular and non-alcoholic fatty liver diseases.
Food Chem Toxicol
September 2011
Article Synopsis
- - The study investigated the impact of a dietary mixture (red grape extract, soy isoflavone, and L-carnitine, collectively known as RISC) on obesity in mice fed a high-fat diet (HFD), showing that RISC effectively reduced body weight and fat accumulation in a dose-dependent way.
- - RISC treatment also lowered plasma leptin levels and increased high-density lipoprotein (HDL) cholesterol, while not affecting low-density lipoprotein (LDL) cholesterol or triglycerides.
- - The findings suggest that RISC may serve as a beneficial additional treatment for obesity and its related health issues, such as cardiovascular diseases and non-alcoholic fatty liver disease.
The effects of a preparation of combined glutathione-enriched yeast (GEY) and rice embryo/soybean (RES) extracts (20:1), GEY/RES, on experimentally induced ethanol hangover were investigated in male Sprague-Dawley rats. To evaluate the preventive effects on hangover, rats were orally administered GEY/RES (50/2.5, 100/5, or 200/10 mg/kg) for 2 weeks.
View Article and Find Full Text PDFAnti-wrinkling effects of the mixture of vitamin C, vitamin E, pycnogenol and evening primrose oil, and molecular mechanisms on hairless mouse skin caused by chronic ultraviolet B irradiation.
Photodermatol Photoimmunol Photomed
October 2007
Background: Naturally occurring antioxidants were used to regulate the skin damage caused by ultraviolet (UV) radiation because several antioxidants have demonstrated that they can inhibit wrinkle formation through prevention of matrix metalloproteinases (MMPs) and/or increase of collagen synthesis.
Objective: We examined the effect of oral administration of the antioxidant mixture of vitamin C, vitamin E, pycnogenol, and evening primrose oil on UVB-induced wrinkle formation. In addition, we investigated the possible molecular mechanism of photoprotection against UVB through inhibition of collagen-degrading MMP activity or through enhancement of procollagen synthesis in mouse dorsal skin.