Publications by authors named "Heo I"

Bayesian piecewise growth mixture models (PGMMs) are a powerful statistical tool based on the Bayesian framework for modeling nonlinear, phasic developmental trajectories of heterogeneous subpopulations over time. Although Bayesian PGMMs can benefit school psychology research, their empirical applications within the field remain limited. This article introduces Bayesian PGMMs, addresses three key methodological considerations (i.

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  • Adsorption-based atmospheric water harvesting (AWH) offers a potential solution for water scarcity in dry regions, but challenges remain in developing efficient adsorbents for low humidity conditions.
  • The study presents a new metal-organic framework (MOF) called FO@HK, which incorporates fluorophenyl oligomers to enhance water capture and allow easy release through sunlight.
  • FO@HK outperforms existing sorbents, achieving significant water harvest rates in outdoor tests, illustrating a promising approach to improve water collection technologies.
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  • - The study examined the relationship between nutritional intake, physical activity (PA), and handgrip strength (HGS) in individuals over 40 with airflow limitation, using data from the 2014 to 2016 Korean National Health and Nutrition Examination Survey.
  • - Results indicated that those who were more physically active and had higher HGS reported greater intakes of food, calories, water, protein, and lipids, with strong correlations found between protein and caloric intake and HGS.
  • - Ultimately, while significant connections were observed, the study concluded that nutritional intake did not serve as an independent factor influencing PA and HGS, suggesting potential indirect effects worth exploring further.
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Inferior vena cava (IVC) injuries can have fatal outcomes and are associated with high mortality rates. Patients with IVC injuries require multiple procedures, including prehospital care, surgical techniques, and postoperative care. We present the case of a 67-year-old woman who stabbed herself in the abdomen with a knife, resulting in an infrarenal IVC injury.

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  • A systematic review was conducted to identify predictors for activating massive transfusion protocols (MTPs) in trauma patients in Korea, as research on this topic had not been previously explored there.
  • The review analyzed ten articles focusing on various clinical assessments, laboratory values, and imaging examinations used to predict MTP activation.
  • Key predictors found to be effective included ROTEM, shock index, MEWS, and lactate levels, indicating the importance of customizing MTP activation strategies according to hospital capabilities and resources.
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Background: Chuna manual therapy (CMT), a Korean manual therapy technique predominantly used for treating low back pain (LBP) and related disorders, lacks well-conceived research focusing on its comparative effectiveness, safety, and economic evaluation, particularly with respect to complex CMT with established CMT diagnostic algorithms. This study aims to illustrate a protocol for a randomized clinical study for comparative effectiveness and cost-effectiveness of complex CMT with simple CMT and usual care.

Methods: This is a protocol for a three-armed, multicenter, assessor-blinded, pragmatic, randomized controlled trial study.

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Electroencephalography (EEG)-based open-access datasets are available for emotion recognition studies, where external auditory/visual stimuli are used to artificially evoke pre-defined emotions. In this study, we provide a novel EEG dataset containing the emotional information induced during a realistic human-computer interaction (HCI) using a voice user interface system that mimics natural human-to-human communication. To validate our dataset via neurophysiological investigation and binary emotion classification, we applied a series of signal processing and machine learning methods to the EEG data.

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This retrospective study aimed to identify the characteristics of Korean medical care utilization in patients with traffic injury (TI) and to explore the clinical effectiveness of Korean medical interventions for TI through a multicenter chart review. This multicenter, retrospective registry study gathered electronic health records from 3 hospitals between January 1, 2018 and December 31, 2021. Data included treatment dates, demographic information, the Korean Standard Classification of Diseases codes, collision data, Korean medicine treatment modalities, and treatment outcomes.

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  • - The study evaluated the FAST HUGS BID checklist's effectiveness in improving clinical outcomes for patients with severe trauma in an ICU setting, comparing data from 2016-2017 (before-FD) and 2019-2020 (after-FD) implementation.
  • - Results showed that the after-FD group experienced significantly lower in-hospital mortality, fewer complications, shorter ICU and hospital length of stay, and reduced mechanical ventilation duration compared to the before-FD group.
  • - The implementation of the FAST HUGS checklist was identified as a key factor in improving patient outcomes, as it correlated with decreased ICU and hospital length of stay and lower in-hospital mortality rates.
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  • * A study was conducted on pigs to evaluate the potential risks of using L-tryptophan as a feed additive, focusing on general toxicity and EMS-related symptoms.
  • * Results showed no toxic effects or EMS symptoms in the pigs, indicating that L-tryptophan and its impurities do not pose safety concerns, allowing its continued use in swine diets throughout all growth stages.
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Ultrasound-guidance is applied during the administration of Korean medicine (KM) interventions to improve the safety and effectiveness of the interventions. Although many case series and reports on the use of ultrasound-guided KM interventions have been reported, no study has investigated the current use of ultrasound-guidance in clinical practice by doctors of Korean medicine (KMDs). An online survey was conducted with questions examining the status of ultrasound-guidance usage among KMDs practicing in various KM clinical settings.

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In this study, the complete mitogenome of the entomopathogenic fungus 15 R, which is highly virulent to aphids and was isolated from Korean soil, was assembled and annotated for three ATP synthase subunits (6, 8, and 9), three cytochrome oxidase subunits (1, , and 3), apocytochrome b (), seven subunits of NADH dehydrogenase (12344L5, and 6), two ribosomal RNAs ( and ), and 19 tRNA genes. Five genes were carrying a total of eight introns, and they may encode ribosomal protein S3, LAGLIDADG and GIY-YIG endonucleases. Phylogenetic analysis based on the mitochondrial nucleotide sequence confirmed that the 15 R is a member of the Clavicipitaceae, and is closely related to the species and The mtDNA base sequence of the 15 R strain reported in this study is thought to be useful for biological resource genetic data.

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Background: Hemorrhage control is a time-critical task, and recent studies have demonstrated that a shorter time to definitive care is positively associated with patient survival and functional outcomes. The concept of direct transport to the operating room was proposed in the 1960s to reduce treatment time. Some trauma centers have developed protocols for direct-to-operating room resuscitation (DOR) programs.

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Objectives: This study aimed to establish clinical evidence for acupuncture by analysing data from trials that demonstrated the efficacy of acupuncture for whiplash-associated disorder (WAD) with the following research question: Is acupuncture treatment effective for symptom alleviation in patients with WAD compared with other usual care?

Design: A systematic review and meta-analysis.

Data Sources: PubMed, Ovid Medline, Embase, The Cochrane Library, China National Knowledge Infrastructure, ScienceOn, KMBASE, Korean Studies Information Service System, Korea Med, Oriental Medicine Advanced Searching Integrated System and Research Information Sharing Service were searched from their inception to 1 October 2023.

Eligibility Criteria: We included randomised controlled trials (RCTs) using acupuncture on patients with WAD.

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Background: Exercise capacity is associated with lung function decline in chronic obstructive pulmonary disease (COPD) patients, but a discrepancy between exercise capacity and airflow limitation exists. This study aimed to explore factors contributing to this discrepancy in COPD patients.

Methods: Data for this prospective study were obtained from the Korean COPD Subgroup Study.

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The recent pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) posed a major threat to global health. Although the World Health Organization ended the public health emergency status, antiviral drugs are needed to address new variants of SARS-CoV-2 and future pandemics. To identify novel broad-spectrum coronavirus drugs, we developed a high-content imaging platform compatible with high-throughput screening.

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Objective: Migraine is a prevalent and disabling neurological disorder affecting a significant proportion of the global population. Although medications are the primary treatment option, their efficacy remains unclear. Thus, alternative therapies such as scalp acupuncture have gained momentum; however, evidence for the effectiveness of scalp acupuncture remains insufficient.

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  • * The EMS outbreak was linked to impurities in L-tryptophan from certain manufacturing processes, not the substance itself.
  • * A study with broiler chickens found no toxic effects or EMS-related symptoms from L-tryptophan in meat, suggesting that L-tryptophan and its impurities are safe as feed additives.
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  • * EMS can affect various organ systems, leading to inflammation in muscles, skin, and lungs, and its association with L-tryptophan supplements has become controversial.
  • * Research has explored the connection between impurities in L-tryptophan products and EMS, but studies have yet to produce clear conclusions on the relationship.
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  • Lythrum salicaria L., known as purple loosestrife, has a history of medicinal use for internal issues and contains beneficial phytochemicals like orientin, which exhibit various health properties.
  • The study aimed to investigate the anti-obesity effects of Lythri Herba, the plant's aerial part, using both cell cultures and high-fat diet-induced mouse models.
  • Results indicated that Lythri Herba water extracts significantly reduced fat accumulation in cells and prevented weight gain in mice, primarily by inhibiting key enzymes involved in fat production.
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Most human proteins lack chemical probes, and several large-scale and generalizable small-molecule binding assays have been introduced to address this problem. How compounds discovered in such "binding-first" assays affect protein function, nonetheless, often remains unclear. Here, we describe a "function-first" proteomic strategy that uses size exclusion chromatography (SEC) to assess the global impact of electrophilic compounds on protein complexes in human cells.

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Background: The objective of this study was to investigate whether alcohol consumption might affect the quality of life (QOL), depressive mood, and metabolic syndrome in patients with obstructive lung disease (OLD).

Methods: Data were obtained from the Korean National Health and Nutrition Examination Survey from 2014 and 2016. OLD was defined as spirometry of forced expiratory volume in 1 second/forced vital capacity <0.

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The ongoing COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is partly under control by vaccination. However, highly potent and safe antiviral drugs for SARS-CoV-2 are still needed to avoid development of severe COVID-19. We report the discovery of a small molecule, Z-Tyr-Ala-CHN, which was identified in a cell-based antiviral screen.

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Superior de-NO activity and N selectivity of the Pd/ZSM-5 catalyst was observed at low temperature (<200 °C) for the selective catalytic reduction of NO by H (H-SCR). Various Pd/ZSM-5 catalysts were prepared by calcinating at different temperatures (e.g.

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  • * This study focuses on creating a new analytical method to detect impurities in meat products quickly using a technique called LC-MS/MS.
  • * The method successfully identifies four specific impurities in just 5 minutes, with high sensitivity and no interference from other substances in the meat, achieving detection limits below 11.2 μg/kg.
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