Analysis of intracranial pressure during and after the infusion test in patients with communicating hydrocephalus.

The cerebrospinal fluid (CSF) infusion test is used to evaluate the dynamics of CSF circulation in patients with communicating hydrocephalus and is based on constant-rate infusion of the normal saline into cerebrospinal fluid space. The aim of the study was to refine methods of the analysis of intracranial pressure (ICP) recorded during and after the infusion test. The mathematical model of cerebrospinal fluid circulation was extended by the equation describing ICP decrease after the infusion.

Slight elevation of baseline intracranial pressure after fluid infusion into CSF space in patients with hydrocephalus.

Objective: To investigate the elevation of resting cerebrospinal fluid (CSF) pressure recorded after a CSF infusion test in patients with hydrocephalus.

Material And Methods: Fifty patients (30 men and 20 women, mean age 68 +/- 13 years) with ventriculomegaly and clinical symptoms of normal pressure hydrocephalus have been studied. Lumbar (56%) or intraventricular (44%) computerized infusion studies were performed to investigate the hydrodynamics of CSF.

[Modeling of cerebrospinal fluid circulation with consideration of a pressure-volume curve in infusion tests of patients with suspected hydrocephalus. Preliminary report].

Aim Of The Study: To verify the model of CSF circulation for both the increasing and decreasing CSF pressure during and after the infusion test.

Material: Computerized infusion tests of 27 patients diagnosed for communicating hydrocephalus in the Department of Neurosurgery, Medical University of Warsaw were analyzed.

Method: Pressure-volume (P-V) curves were plotted separately for ascending and descending phases of the test for comparison purposes.

The relation between cerebral blood flow velocities as measured by TCD and the incidence of delayed ischemic deficits. A prospective study after subarachnoid hemorrhage.

Patients (n = 127) with aneurysmal subarachnoid hemorrhage (SAH) were examined by transcranial Doppler ultrasonography (TCD) in a prospective study to follow the time course of the posthemorrhagic blood flow velocity in both the middle cerebral artery (MCA) and in the anterior cerebral artery (ACA). Results were analysed to reveal their relationship and predictive use with respect to the occurrence of delayed ischemic deficits. Mean flow velocities (MFV) higher than 120 cm sec(-1) in MCA and 90 cm sec(-1) in ACA were interpreted as indicative for significant vasospasm.