Impact of cardiometabolic factors on retinal vasculature: A 3 × 3, 6 × 6 and 8 × 8-mm ocular coherence tomography angiography study.

Background: Ocular coherence tomography angiography (OCTA) is available in varying size and resolution. We sought to characterise associations of cardiometabolic factors with retinal microvascular changes using 3 × 3, 6 × 6 and 8 × 8-mm OCTA scans to determine differences in detection with varying scan size.

Methods: Cross-sectional study of 247 cardiovascular patients from a single-centre tertiary-care hospital.

Visual outcomes following vitrectomy for diabetic retinopathy amongst Indigenous and non-Indigenous Australians in South Australia and the Northern Territory.

Importance: Visual outcomes following diabetic vitrectomy have not previously been studied in an Australian population.

Background: This analysis aimed to determine the rate of, and factors associated with visual success following diabetic vitrectomy performed for Indigenous and non-Indigenous Australians, and investigate factors predisposing to early progression to diabetic retinopathy (DR) requiring vitrectomy.

Design: Retrospective, population-based audit.

Biochemical analysis of the living human vitreous.

Background: To date, our understanding of the biochemical composition of the living human vitreous relies on extrapolations from animal or human post-mortem studies.

Methods: This was a cross-sectional study of vitreous samples from 27 individuals scheduled for retinal surgery within a tertiary hospital. From each vitreous sample, the concentrations of sodium, potassium, chloride, calcium, magnesium, glucose, lactate, β- hydroxybutyrate, copper, zinc, selenium, iron, ferritin and transferrin and osmolality were measured.

Antemortem vitreous potassium may strengthen postmortem interval estimates.

The purpose of this letter is to highlight that postmortem interval estimates using vitreous potassium concentrations may be further optimised by calibration against antemortem vitreous samples.

Glucose-induced temporary visual recovery in primary open-angle glaucoma: a double-blind, randomized study.

Purpose: To investigate the effect of topical glucose on visual parameters in individuals with primary open-angle glaucoma (POAG).

Design: Double-blind, randomized, crossover study.

Participants: Nondiabetic pseudophakic patients with definite POAG were recruited; 29 eyes of 16 individuals participated in study 1.

Perspective on ophthalmic support in countries of the developing world.

There are over 300 million people living in the world today who are visually impaired and a further 45 million who are blind. The large majority (90%) of these people live in developing countries, and up to 75% of blindness are avoidable. With cataracts being the major cause of blindness and visual impairment, many ophthalmic aid programmes are aimed at alleviating the enormous burden caused by this readily treatable disease.

Pilot randomized trial of a nanopulse retinal laser versus conventional photocoagulation for the treatment of diabetic macular oedema.

Background:   To assess the efficacy of a new nanopulse laser, retinal regeneration therapy for the treatment of diabetic macular oedema.

Design:   Randomized, non-inferiority, trial.

Participants:   20 eyes of 17 subjects in the retinal regeneration therapy group and 18 eyes of 14 subjects in the conventional group were analysed.

Killing two birds with one stone: the potential effect of cataract surgery on the incidence of primary angle-closure glaucoma in a high-risk population.

Background: To estimate the proportion of cataract surgery performed at various visual acuity and lens opacity thresholds that would coincidentally treat early angle-closure disease, and to estimate the effect of this surgery on the incidence of primary angle-closure glaucoma.

Design: Cross-sectional, population-based survey in Meiktila, Myanmar.

Participants: Total of 2076 inhabitants, 40 years of age and over were included.

Sutureless vitrectomy.

Sutureless vitrectomy has rapidly been accepted as an essential part of a vitreoretinal surgical setup. The size and structure of the wound along with near intact conjunctival covering makes the incision self-sealing and safe. This allows the vitrectomy instruments to be used without creating an initial limited peritomy to expose bare sclera, and obviates the need for sutures at the end of the procedure.

Cataract surgical coverage and self-reported barriers to cataract surgery in a rural Myanmar population.

Purpose: The aim of this study is to determine the cataract surgical coverage and investigate the barriers to cataract surgery as reported by those with cataract-induced visual impairment in rural Myanmar.

Methods: A cross-sectional, population-based survey of inhabitants 40 years of age and over from villages in the Meiktila District (central Myanmar); 2481 eligible participants were identified and 2076 participated. Data recording included corrected visual acuity, dilated slit lamp examination and stereoscopic fundus examination.

Corneal thickness and intraocular pressure in a nonglaucomatous Burmese population: the Meiktila Eye Study.

Objective: To determine correlates of central corneal thickness (CCT) and its relationship to intraocular pressure (IOP) in a Burmese population.

Methods: We performed a population-based survey of inhabitants 40 years or older in Myanmar; of 2076 participants, data from 1909 nonglaucomatous subjects who underwent ultrasound pachymetry and Goldmann applanation tonometry were analyzed. Linear mixed effects models adjusting for nonindependence of right and left eye data were constructed.

Awareness of diabetic eye disease among general practitioners and diabetic patients in Yangon, Myanmar.

Background: Diabetes is an increasing problem in Myanmar with more than three million people affected. There are no data on awareness of diabetic retinopathy among the general practitioners (GPs) or diabetic population of Myanmar. This study aims to evaluate the awareness of diabetes-related eye disease among GPs and diabetic patients in Yangon, Myanmar.

Association between stature, ocular biometry and refraction in an adult population in rural Myanmar: the Meiktila eye study.

Purpose: To study the association between adult stature and ocular biometric parameters and refraction.

Methods: In a population-based cross-sectional ophthalmic survey of 2418 adults (> or = 40 years old) living in the rural villages in central Myanmar, height and weight were measured using a standardized protocol, and body mass index was calculated. Non-cycloplegic refraction and corneal curvature were determined by an autorefractor.

Risk factors for primary open-angle glaucoma in a Burmese population: the Meiktila Eye Study.

Purpose: To report the risk factors associated with primary open-angle glaucoma (POAG) in the Burmese population.

Methods: The Meiktila Eye study, a population-based cross-sectional study, included inhabitants 40 years of age and over from villages in the Meiktila District. Of 2481 eligible participants identified, 2076 participated in the study and sufficient examination data to diagnose glaucoma in at least one eye was obtained in 1997 participants.

Central corneal thickness among Aboriginal people attending eye clinics in remote South Australia.

Purpose: To determine the central corneal thickness (CCT) and its demographic associations among Aboriginal people attending eye clinics in remote South Australia.

Methods: A clinic-based cross-sectional study was conducted involving opportunistic sampling of patients. Eligible participants underwent measurement of CCT by ultrasound pachymetry.

Distance refractive error among Aboriginal people attending eye clinics in remote South Australia.

Purpose: To determine the prevalence of distance refractive error among Aboriginal people attending eye clinics in remote South Australia.

Methods: A clinic-based cross-sectional study was conducted that involved opportunistic sampling of Aboriginal people attending eye clinics in remote South Australia. There were 189 individuals who were invited to participate in the study all of whom underwent ophthalmic examination.

Improving patient satisfaction through information provision.

Background: This study aims to determine the sociodemographic characteristics of the Ophthalmology Outpatient Clinic at the Royal Adelaide Hospital, to ascertain satisfaction levels with aspects of care, and determine if patient satisfaction levels can be increased by the provision of information letters prior to appointment.

Methods: New patients attending Ophthalmology Outpatient Clinic were surveyed regarding sociodemographic information and satisfaction levels. Participants received an introductory letter prior to their clinic appointment, and were compared with controls.

Prevalence of trachoma-related trichiasis and corneal opacity in rural Myanmar: the Meiktila Eye Study.

Objective: To describe the prevalence of trachomatous trichiasis and corneal opacity (CO) within central Myanmar.

Design: Population-based cross-sectional ophthalmic survey.

Participants: Random, stratified, cluster sampling of the inhabitants > or =40 years of age from villages in the Meiktila District was performed; 2481 eligible participants were identified and 2076 participated in the study.

Atrial fibrillation following subconjunctival injection of mydricaine number 02.

Mydricaine is a mydriatic agent used as a subconjunctival injection to maintain perioperative mydriasis. The drug consists of a mixture of 1.3 mg atropine sulphate, 0.