Comparison of estimated glomerular filtration rate with estimated creatinine clearance in the dosing of drugs requiring adjustments in elderly patients with declining renal function.

Background: The National Kidney Foundation's practice guidelines for chronic kidney disease recommend using the Modification of Diet in Renal Disease (MDRD) equation for calculating the estimated glomerular filtration rate (GFR).

Objective: The purpose of this article was to compare the use of this estimated GFR with estimated creatinine clearance (CrCl) calculated using the Cockcroft-Gault equation (CG(CrCl)-Eq) in the dosing of drugs requiring adjustments in elderly patients with declining renal function. Existing as well as new serum creatinine assay standards were used.

Influences on pharmacy students' decision to pursue a doctor of pharmacy degree.

Objectives: To determine what influenced pharmacy students to pursue a career in pharmacy and how those influences varied among different racial groups.

Methods: A 30-question survey instrument was developed and administered to doctor of pharmacy (PharmD) students at the University of Georgia and Florida A&M University. Data were analyzed to identify differences between students at different institutions and of different racial groups.