Tear Film miRNAs and Their Association With Human Dry Eye Disease.

Purpose: miRNAs can regulate inflammatory pathways. The purpose of this work was to determine if inflammatory-related tear film miRNAs are associated with extracellular vesicles (EVs) in human non-Sjögren's Syndrome dry eye disease (DED) participants.

Methods: Five DED and 5 non-DED human participants were recruited.

Adenovirus infection activates akt1 and induces cell proliferation in pancreatic islets1.

Background: : Accumulated evidence has shown that insulin producing beta-cells in pancreatic islets have the limited potential to regenerate. Adenoviruses have been widely employed to deliver genes of interest into pancreatic islets. This study was aimed at investigating whether adenovirus infection has any impact on the potential of beta-cell proliferation.