Do it fast! Early access to specialized care improved long-term outcomes in rheumatoid arthritis: data from the REAL multicenter observational study.

Background: Early rheumatoid arthritis (RA) offers an opportunity for better treatment outcomes. In real-life settings, grasping this opportunity might depend on access to specialized care. We evaluated the effects of early versus late assessment by the rheumatologist on the diagnosis, treatment initiation and long-term outcomes of RA under real-life conditions.

Landscapes of Biochemical Warfare: Spatial Self-Organization Woven from Allelopathic Interactions.

Evidence shows that diversity and spatial distributions of biological communities are largely driven by the race of living organisms in their adaptation to chemicals synthesized by their neighbors. In this report, the emergence of mathematical models on pure spatial self-organization induced by biochemical suppression (allelopathy) and competition between species were investigated through numerical analysis. For both random and patched initial spatial distributions of species, we demonstrate that warfare survivors are self-organized on the landscape in Turing-like patterns driven by diffusive instabilities of allelochemicals.

Development of superabsorbent hydrogel based on Gum Arabic for enhanced removal of anxiolytic drug from water.

The growing consumption of anxiolytic drugs like diazepam (DZP) has aggravated the problem of persistent organic pollutants in water. Due to its characteristics, the removal of DZP from water and wastewater is a challenging task. As an effort to deals with this issue, in this study, we report the development of a hydrogel based on Gum Arabic (GA) grafted with poly(acrylic acid) (GA-g-PAAc) to be used in the adsorptive removal of DZP from water.

One-Year Clinical Outcome of Inspiron Stent in All-Comers Population (Analysis from 790 Consecutive Patients).

Aims: The goal of this study was to evaluate the performance of the Inspiron coronary stent (Scitech Medical™, Goiás, Brazil). The Inspiron sirolimus-eluting stent uses an ultrathin L-605 cobalt-chromium alloy with a 75 m strut thickness platform coated with an abluminal biodegradable polymer. The polymer is eliminated from the body through the tricarboxylic acid cycle in 6-9 months, releasing 80% of the drug within 30 days after its deployment.

Magnetoreception in multicellular magnetotactic prokaryotes: a new analysis of escape motility trajectories in different magnetic fields.

Magnetotactic microorganisms can be found as unicellular prokaryotes, as cocci, vibrions, spirilla and rods, and as multicellular organisms. Multicellular magnetotactic prokaryotes are magnetotactic microorganisms composed by several magnetotactic bacteria organized almost in a spherical helix, and one of the most studied is Candidatus Magnetoglobus multicellularis. Several studies have shown that Ca.

Comprehensive Chemical Characterisation of Byzantine Glass Weights.

The understanding of the glass trade in the first millennium CE relies on the characterisation of well-dated compositional groups and the identification of their primary production sites. 275 Byzantine glass weights from the British Museum and the Bibliothèque nationale de France dating to the sixth and seventh century were analysed by LA-ICP-MS. Multivariate statistical and graphical data analysis discriminated between six main primary glass types.

Postemetic rupture of the esophagus: Boerhaave's syndrome.

Postemetic rupture of the esophagus, also known as spontaneous rupture or Boerhaave's syndrome, was first described by Herman Boerhaave in 1724. This is a severe disease that causes high mortality rates and is difficult to diagnose not only because it is rare but also because it is frequently confused with other severe clinical conditions, such as acute myocardial infarction, perforated peptic ulcer, and acute pancreatitis. Herein, we describe three cases of patients with this syndrome.