Publications by authors named "Henrique Lepine"

Background: Ependymomas account for 6% to 10% of childhood central nervous system tumors. This study aimed to evaluate the safety and efficacy of proton radiotherapy in intracranial ependymoma patients.

Methods: We performed a systematic review and single-arm meta-analysis.

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Article Synopsis
  • A meta-analysis was conducted to evaluate the effectiveness of Reverse Trendelenburg (RevTren) and Trendelenburg (Tren) surgical positions versus standard dorsal lithotomy in reducing ureteral stone migration during ureteroscopic laser lithotripsy.
  • The study reviewed 137 articles, ultimately including 8 that involved 1,374 patients, highlighting that RevTren significantly reduced stone migration and improved success rates, while Tren increased stone success despite promoting migration to upper calyces.
  • Both alternative positions offer notable benefits over the standard method without increasing complications, suggesting they can be safely integrated into clinical practice for better patient outcomes.
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Decompressive craniectomy is used to alleviate intracranial pressure in cases of traumatic brain injury and stroke by removing part of the skull to allow brain expansion. Traditionally, this procedure is followed by a watertight dural suture, although evidence supporting this method is not strong. This meta-analysis examines the feasibility of the open-dura (OD) approach versus the traditional closed-dura (CD) technique with watertight suturing.

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Introduction: The optimal temperature of irrigation solution in patients undergoing PCNL is still unclear. Accordingly, this study aims to investigate the effects of different irrigation solution temperatures (cold/room temperature irrigation fluid versus warm/body temperature fluid). Our primary endpoint was hypothermia rate.

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Background: Success rates in endourological procedures, notably percutaneous nephrolithotomy (PCNL) and ureteroscopy (URS), have demonstrated suboptimal outcomes, leading to more reinterventions and radiation exposure. Recently, the use of intraoperative computed tomography (ICT) scans has been hypothesized as a promising solution for improving outcomes in endourology procedures. With this considered, we conducted a comprehensive systematic review and meta-analysis encompassing all available studies that evaluate the impact of the use of intraoperative CT scans on surgical outcomes compared to conventional fluoroscopic-guided procedures.

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