Publications by authors named "Henrik Laurits Bjerre"

Article Synopsis
  • The study aimed to explore labor market participation in working-age heart failure patients before and after receiving cardiac resynchronization therapy (CRT), noting its potential benefits for recovery and quality of life.
  • Researchers analyzed data from 546 patients who underwent CRT in Central Denmark from 2000 to 2017, focusing on their employment status from one year before to five years after the procedure.
  • Results showed that while active employment dropped significantly before CRT, it increased to 31% one year post-implantation, with labor market participation influenced by factors like age, education level, and the presence of other health conditions.
View Article and Find Full Text PDF

Aims: Several studies have evaluated the use of electrically- or imaging-guided left ventricular (LV) lead placement in cardiac resynchronization therapy (CRT) recipients. We aimed to assess evidence for a guided strategy that targets LV lead position to the site of latest LV activation.

Methods And Results: A systematic review and meta-analysis was performed for randomized controlled trials (RCTs) until March 2023 that evaluated electrically- or imaging-guided LV lead positioning on clinical and echocardiographic outcomes.

View Article and Find Full Text PDF

Background And Purpose: Cardiac implantable electronic device (CIED) malfunctions can be induced by secondary neutron dose from spot-scanning proton therapy. A recent in-vitro study investigating secondary neutron dose to CIEDs up to 7 mSv per fraction found that exposure of secondary neutrons in this range was clinically manageable. This study presents decision algorithms proposed by a national expert group for selection of patients with breast and head & neck (H&N) cancer with CIEDs adjacent to target for proton therapy based on the 7 mSv threshold.

View Article and Find Full Text PDF

Purpose: Cardiac implantable electronic devices (CIED) are sensitive to scattered secondary neutrons from proton beam irradiation. This experimental in vitro study investigated risk of CIED errors during pencil beam proton therapy.

Methods And Materials: We used 62 explanted CIEDs from 4 manufacturers; 49 CIEDs were subjected to a simulated clinical protocol with daily 2 Gy relative biological effectiveness fractions prescribed to the phantom.

View Article and Find Full Text PDF

The role of the direct renin inhibitor aliskiren in hypertension is not fully established and use of aliskiren in diabetic patients is especially controversial. A systematic review investigating both short-term diastolic and systolic blood pressure (DBP and SBP) reduction and long-term cardiovascular outcomes has not been conducted. Therefore, we aimed to fill this gap by investigating BP reduction, major cardiovascular outcomes, and mortality of aliskiren compared to other antihypertensive therapy.

View Article and Find Full Text PDF