Publications by authors named "Henrik Funke"
Alginate Microfiber System for Expansion and Direct Differentiation of Human Embryonic Stem Cells.
Tissue Eng Part C Methods
September 2016
Article Synopsis
- Pluripotent human embryonic stem cells (hESCs) are highlighted as a renewable source for regenerative medicine, necessitating scalable culture methods for cell propagation.
- In this study, hESCs were encapsulated in calcium alginate microfibers, allowing for growth in small aggregates under controlled conditions, leading to successful cell expansion and maintenance of pluripotency across five passages.
- The method demonstrated effective differentiation of the hESC line HUES7 into liver-like cells, indicating the potential of the alginate microfiber system for long-term, defined culture of pluripotent stem cells.