Publications by authors named "Henrik Boye Thybo Christesen"
Background: Vitamin D status in pregnancy may affect offspring neurodevelopment.
Objective: The objective was to investigate the association between serum 25-hydroxyvitamin D in cord blood and pregnancy and symptoms of attention-deficit hyperactivity disorder in 5-year-old offspring.
Method: In Odense Child Cohort, Denmark, 944 mother-child pairs had data on pregnancy or cord serum 25-hydroxyvitamin D and parent-rated attention-deficit hyperactivity disorder symptom score by Child Behavior Checklist for ages 1.
Article Synopsis
- Prenatal and early postnatal exposure to perfluoroalkyl substances (PFAS) is linked to lower bone mineral density (BMD) in children, based on a study involving health data from 881 pregnant women and their children in Denmark.
- The study measured PFAS levels in both mothers and children, finding that higher concentrations of PFAS were associated with reduced bone mineral content (BMC) and lower BMD Z-scores at age 7, though not all findings were statistically significant.
- Results indicated that postnatal PFAS exposure had a stronger negative impact on BMD than prenatal exposure, suggesting potential long-term consequences for bone health established during early childhood.
Objectives: Animal studies indicate a key role for vitamin D in brain development and function, but observational studies in humans only suggests a borderline positive association between prenatal vitamin D exposure and cognitive development in the offspring. Knowledge gaps include insights in exposure time window and differences by sex for the association. We aimed to investigate the association between blood concentrations of serum 25-hydroxyvitamin D measured at four different time points and intelligence quotient score at the age of 7 years, including analyses spilt by child sex.
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