Publications by authors named "Henriette Meyer zu Schwabedissen"
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Synopsis of recent research by authors named "Henriette Meyer zu Schwabedissen"
- Henriette Meyer Zu Schwabedissen's recent research primarily focuses on the pharmacokinetics and drug interactions involving organic anion transporting polypeptides (OATPs), emphasizing their role in mediating drug absorption and metabolism, particularly for drugs like atorvastatin and ezetimibe.
- Her studies highlight the potential for biomarkers, such as coproporphyrin isomers, to predict OATP-mediated drug interactions, as evidenced by increased serum levels of these biomarkers with specific drug treatments and the influence of genetic factors in knockout and humanized rat models.
- Additionally, her work addresses the implications of common drug metabolism issues, including the effects of strong CYP3A4 inhibitors, the clinical evaluation of OATP1B1 interactions, and the need for improved drug information relevant to pediatric use, indicating a health systems-oriented approach to pharmacological research.
