Publications by authors named "Henrietta Morrell-Davies"
Article Synopsis
- Obesity leads to lipid accumulation in heart cells (cardiomyocytes), causing stress and heart damage, which can result in heart failure.
- Researchers found that PAK3 levels are higher in the hearts of obese individuals and in mice that are stressed by diet, making them more prone to heart issues due to toxic lipid buildup.
- Knocking down PAK3 can reduce fat-induced toxicity in heart cells, suggesting that targeting PAK3 might be a potential treatment for obesity-related heart problems.
