Publications by authors named "Henri Clavaud"

Interest Of The Work: Multiple sclerosis (MS) disease modifying therapies (DMT) utilization increased during the last decade with the approval of new drugs. Symptomatic treatments also play an important role. Describing time trends and demographic characteristics for DMT and symptomatic treatments utilization in population-based MS patients will lead to a better knowledge of the resources distribution.

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Article Synopsis
  • Two studies in France found that multiple sclerosis prevalence shows a geographic gradient, but only among farmers, leading researchers to investigate this trend in independent workers.
  • Analysis of data from over 4 million independent workers revealed that the prevalence of multiple sclerosis increases from southwest to northeast France, with a significant correlation to geographic location.
  • The differences in geographic distribution among different worker populations suggest that factors like adult mobility in the workforce could influence the prevalence of the disease, rather than environmental factors alone.
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Aim: The purpose of this paper is to describe and analyze the diagnosis and treatment of age-related macular degeneration (AMD) based on current guidelines.

Methods: A study was conducted on a sample of French AMD patients covered by the RSI (public health insurance for self-employed workers), who received a first reimbursement in 2008 for treatments including verteporfin (Visudyne®), pegaptanib (Macugen®) and/or ranibizumab (Lucentis®). Data were collected retrospectively from the ophthalmologist by the medical adviser.

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Objectives: Physicians frequently fail to detect mental health disorders in patients consulting them. This study tests the hypothesis that patients repeatedly prescribed analgesics or antiinflammatory drugs or X-ray examinations for unexplained somatic symptoms are at higher risk of antidepressant treatment, independent of physical comorbidity.

Methods: This case-control study is based on health reimbursement data for self-employed artisans and shopkeepers.

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