Publications by authors named "Henny M Schulten"
Soluble Jagged-1 inhibits neointima formation by attenuating Notch-Herp2 signaling.
Arterioscler Thromb Vasc Biol
May 2011
Objective: Notch has been implicated in neointima formation as reflected by increased Notch/Jagged expression on vascular injury and the promigratory effect of Notch signaling on smooth muscle cells. Soluble Jagged-1 (sJag1) has been shown to inhibit Notch signaling in vitro; however, its capacity to suppress neointima formation remains unknown.
Methods And Results: Balloon injury of rat carotid arteries induced Notch1, Notch3, and Jagged-1 expression at days 3 and 14 postinjury.