Introduction: Sources of infection of most cases of community-acquired Legionnaires' disease (CALD) are unknown.
Objective: Identification of sources of infection of CALD.
Setting: Berlin; December 2016-May 2019.
Aims: Recent studies have suggested that human extracardiac progenitor cells are capable of differentiating into cardiomyocytes. In animal studies, myocardial infarction attracted bone marrow stem cells and enhanced their differentiation into cardiomyocytes. Based on these findings, we hypothesised that myocardial infarction stimulates the invasion of progenitor cells and their differentiation into endothelial and cardiac cells in the human heart.
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