Potency of anti-trematode in inhibiting cathepsin-2L and cathepsin-5L of using homology, docking, and molecular dynamics.

Background: Cathepsin-L (FhCL) is a group of enzymes that most flukes express and secreted significantly in parasite-host interactions. Researches are focusing on antigens released by as one of the keys to understanding immunologic pathways in parasite infection and targets for anthelmintics. Efforts to suppress FhCL function through vaccination or therapy using anthelmintic drugs are key factors in controlling field-level trematode infections.

prediction of flavan-3-ol as a bioactive compound of as a potential drug against angiostrongylus eosinophilic meningitis.

Background And Aim: Angiostrongylus eosinophilic meningitis is caused by larvae of the rat lungworm . It manifests as meningitis, radiculitis, cranial nerve abnormalities, and encephalitis, which can be fatal. A flavan-3-ol compound isolated from the bark of Scheff.

Cuticular surface damage of adult worms treated with betel nuts extract .

Aim: The objective of this research was to evaluate the cuticular surface damage of adult worms treated with ethanolic extract of betel nuts .

Materials And Methods: Phytochemical screening was done using FeCl, Wagner and Dragendorff reagents, NaOH, MgHCl, and Liebermann-Burchard reaction test. Amount of 16 worms were segregated into four groups with three replicates.