Publications by authors named "Henna Sarja"
Article Synopsis
- Scientists wanted to see if a drug called diazoxide can protect the heart during a time when it doesn’t get enough blood (called acute myocardial ischemia).
- They tested this on 12 piglets, giving some of them diazoxide before blocking a heart artery for 40 minutes to mimic the problem.
- The results showed that the piglets given diazoxide had less cell damage in their hearts and better heart function compared to those that did not get the drug.
Background: Paraplegia is one of the most severe complications occurring after the repair of thoracic and thoracoabdominal aortic aneurysms. Remote ischemic preconditioning (RIPC) has been shown to mitigate neurologic damage, and this study assessed its efficacy in preventing spinal cord ischemia.
Methods: The study randomized 16 female pigs into an RIPC group (n = 8) and a control group (n = 8).