The Phenotype of Celiac Disease Has Low Concordance between Siblings, Despite a Similar Distribution of HLA Haplotypes.

The factors determining the presentation of celiac disease are unclear. We investigated the phenotypic concordance and the distribution of human leukocyte antigen (HLA) risk haplotypes in affected siblings. One hundred sibling pairs were included.

Long-term follow-up in adults with coeliac disease: Predictors and effect on health outcomes.

Introduction: Guidelines recommend regular follow-up in coeliac disease, but effect of this on long-term outcomes remains unclear.

Aims: To evaluate predictors and significance of long-term follow-up.

Methods: 677 previously diagnosed coeliac patients were recruited for a nationwide health survey.

Predictors and Significance of Incomplete Mucosal Recovery in Celiac Disease After 1 Year on a Gluten-Free Diet.

Objectives: In celiac disease, a follow-up biopsy taken 1 year after diagnosis is considered important in monitoring histological recovery. In many cases, recovery is incomplete, and the clinical significance of this is poorly understood. We now investigated associated factors and the significance of imperfect histological recovery in patients in whom the follow-up had been completed.