Publications by authors named "Henk-Thijs Brandsma"

Article Synopsis
  • The study aimed to evaluate how effective prophylactic mesh is for preventing parastomal hernias in end colostomy patients, ultimately contributing to European clinical guidelines.* -
  • The meta-analysis included 12 randomized trials, showing that while quality of life (QoL) was unaffected by the use of mesh, it significantly reduced the incidence of parastomal hernias (risk reduction OR = 0.33).* -
  • No significant differences were found in surgery requirements or severe complications associated with mesh use, suggesting that while the mesh helps reduce hernia rates, it doesn’t impact QoL or lead to more serious surgical issues.*
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Article Synopsis
  • A new guideline has been developed for preventing parastomal hernias, prompted by evidence supporting the use of prophylactic mesh and advancements in guideline methods.
  • An interdisciplinary panel, including surgeons, nurses, and patients, employed a systematic review and meta-analysis to create trustworthy recommendations based on GRADE standards.
  • The guideline recommends using prophylactic mesh for patients with end colostomies, particularly those at high risk, while acknowledging moderate evidence certainty for parastomal hernia prevention and identifying areas for future research.
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Objective: The aim of this study was to determine if prophylactic mesh placement is an effective, safe, and cost-effective procedure to prevent parastomal hernia (PSH) formation in the long term.

Background: A PSH is the most frequent complication after stoma formation. Prophylactic placement of a mesh has been suggested to prevent PSH, but long-term evidence to support this approach is scarce.

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Background: Colorectal peritoneal metastases (PM) are often diagnosed in an advanced disease stage. Cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) improve survival of patients with colorectal PM, although most benefit is seen in patients with limited peritoneal disease. Advanced imaging techniques might improve the detection of PM, potentially leading to earlier diagnosis and improved cytoreduction.

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Objective: The aim of this study was to investigate the incidence of parastomal hernias (PSHs) after end-colostomy formation using a polypropylene mesh in a randomized controlled trial versus conventional colostomy formation.

Background: A PSH is the most frequent complication after stoma formation. Symptoms may range from mild abdominal pain to life-threatening obstruction and strangulation.

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Background: Parastomal hernia is a common complication of a colostomy. Ultimately, one-third of patients with a parastomal hernia will need surgical correction due to frequent leakage or life-threatening bowel obstruction or strangulation. However, treatment remains a challenge resulting in high recurrence rates.

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