Publications by authors named "Henk Louagie"
Int J Lab Hematol
October 2024
Article Synopsis
- Accurate measurement of the BCR::ABL1 fusion gene is crucial for managing chronic myeloid leukemia (CML), most commonly found as the p210 variant due to certain mRNA junctions.
- The study analyzed 25 CML samples using two accredited centers with qPCR methods and compared results using advanced techniques like ddPCR, revealing significant differences in measurement accuracy.
- Findings highlight that quantification differences may vary by center, impacting patient follow-up, and suggest that using specific standard curves or absolute quantification methods can mitigate these discrepancies.
