Harmonization of the ICHOM Quality Measures to Enable Health Outcomes Measurement in Multimorbid Patients.

To update the sets of patient-centric outcomes measures ("standard-sets") developed by the not-for-profit organization ICHOM to become more readily applicable in patients with multimorbidity and to facilitate their implementation in health information systems. To that end we set out to (i) harmonize measures previously defined separately for different conditions, (ii) create clinical information models from the measures, and (iii) restructure the annotation to make the sets machine-readable. First, we harmonized the semantic meaning of individual measures across all the 28 standard-sets published to date, in a harmonized measure repository.