Innovative 3D-printed porous tantalum cage with non-window design to accelerate spinal fusion: A proof-of-concept study.

An interbody fusion cage is crucial in spine fusion procedures, serving to restore physiological vertebral alignment and reestablish spinal stability. However, conventional fusion cages often face challenges related to insufficient osteointegration and the requirement for substantial bone grafting, which may result in incomplete fusion and prolonged recovery periods. In this study, we harnessed the osteointegration advantages of tantalum (Ta), in conjunction with advanced 3D printing technology, to develop a novel non-window-type Ta cage.

Morphological characteristics and phylogenetic analyses revealed five new species (Basidiomycota) from Southwestern China.

In the present study, five new wood-inhabiting fungal species, (Stereaceae, Russulales), (Punctulariaceae, Corticiales), (Auriculariaceae, Auriculariales), (Incertae sedis, Russulales), and (Punctulariaceae, Corticiales), collected from southern China, are proposed based on a combination of morphological features and phylogenetic evidence. is characterized by membranaceous and smooth basidiomata with white to cream surface and ellipsoid and verrucose basidiospores (9-11 × 5-7 µm); is characterized white to buff, membranaceous basidiomata and ellipsoid, thin-walled and smooth basidiospores (7-8 × 4.5-5.

Controllable growth of wafer-lever MoS films by using heating sulfurization treatment.

Few-layer MoS films have garnered significant attention as promising materials for electronic devices and sensors due to their exceptional carrier mobility and tunable bandgap. Although various chemical vapor deposition (CVD) techniques have been employed to fabricate few-layer MoS films, there remains a need for film homogeneity, continuity, and crystalline quality improvements. This research used the TVS method to fabricate large-scale few-layered MoS films.

Matrix-assisted laser desorption/ionization mass spectrometry imaging analysis revealed the spatial distribution of metabolites during at different growth periods.

(ZSS), a medicinal food, is one of the most popular Chinese medicinal herbs, known for its rich bioactive ingredients, such as terpenoids and flavonoids. The content of these bioactive ingredients in ZSS varies with age. However, the distribution of these bioactive ingredients throughout the developmental phases of ZSS-white maturity (S1), firm ripening (S2), and full ripening (S3)-and within specific tissues like the cotyledon, endosperm, and radicle, has not yet been determined.

Genome-wide identification and expression profile analysis of TALE superfamily genes under hormone and abiotic stress in maize ( L.).

Introduction: The three-amino-acid-loop-extension (TALE) of the homeobox superfamily genes plays important roles in plant growth, development, and responses to environmental stress. Although TALE members have been identified in various species, they have not been systematically characterized in maize and their expression profiles under ABA hormone and abiotic stress are unknown.

Methods: Bioinformatics methods were employed to identify the TALE family genes in the maize genome.

Bench Surgery with Robot-assisted Kidney Autotransplantation for Complex Kidney Tumors: Technique and Outcomes from a Single Center.

Background And Objective: Bench surgery (BenS) with kidney autotransplantation serves as an alternative to nephron-sparing surgery (NSS) for patients harboring high-complexity renal tumors that are ineligible for in situ partial nephrectomy (PN). However, the experience of BenS with robot-assisted kidney autotransplantation (RAKAT) has been scarce in such cases. Here, we describe the operative techniques, and functional and oncological outcomes of BenS with RAKAT.

PK 11195 derivatives: exploring the influence of amide and heterocyclic substitution on A147T TSPO discrimination.

The translocator protein (TSPO) is an 18 kDa protein on the outer mitochondrial membrane. It has gained significant interest in recent years for its potential as a therapeutic target and imaging biomarker, particularly in neuroinflammation, cancer, and central nervous system disorders (CNS). Clinical translation of ligands has been complicated by the presence of a common single nucleotide polymorphism (A147T TSPO), at which many disclosed TSPO ligands lose affinity.

Corrigendum: Correlation between CT-derived fractional flow reserve and myocardial strain in ischemic heart disease patients with single coronary artery stenosis assessed based on CCTA.

[This corrects the article DOI: 10.3389/fcvm.2025.

Treatment of a rare and severe infection of central nervous system by : A case report.

Background: -induced acute parasitic infection is a rare food-borne disease in clinical practice. Lack of its specific laboratory markers and subsequent difficulty in detecting pathogens cause high misdiagnosis and missed diagnosis rates.

Case Summary: A 20-year-old male developed persistent neck and back pain after consuming raw snail meat, followed by urinary retention and low fever.

Practical 4.7 V solid-state 18650 cylindrical lithium metal batteries with fabricated localized high-concentration polymer electrolytes.

fabricated gel polymer electrolytes (GPEs), characterized with superior interfacial properties and large-scale processibility, represent a promising electrolyte system for high-performance lithium metal batteries (LMBs). Herein, we propose an fabricated high-voltage GPE featuring a localized high-concentration solvation structure (LHCE-GPE). This tailored special solvation structure within a polymer matrix promotes the formation of an electrochemically robust electrode-electrolyte interphase.

Will the next pandemic be caused by coronavirus again? An interview with George Fu Gao.

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Blockade of TSP-1/CD47 signal axis promotes donor hematopoietic engraftment by improving SEC/MK niche function.

Thrombospondin-1 (TSP-1)/CD47 signaling induces cell death and inhibits angiogenesis. Here, we investigated the possibility of improving donor engraftment by blocking the TSP-1/CD47 pathway in mouse models of total body irradiation (TBI)-conditioned syngeneic hematopoietic stem cell transplantation (HSCT). Our findings revealed that HSCT engraftment was improved in mice deficient in CD47 ( ) or TSP-1 ( ) compared to wild-type (WT) mice.

Research on a Concentration Detection Method for Turbid Media Based on Multipath Combination.

In order to improve the accuracy of concentration detection in turbid media, this study proposes a solution concentration detection method based on a variable-angle wedge-shaped sample cell. Each angle of the wedge-shaped sample cell corresponds to a specific optical path combination. By measuring at multiple wedge angles, we can expand a variety of optical path combinations, providing more information about the turbid media.

Simulation and Analysis of a Novel Hydrogen Liquefaction Process Based on the Liquid Nitrogen and Helium Joule-Brayton Cycle.

To facilitate the design, analysis, and optimization of the hydrogen liquefaction system, this study developed a MATLAB-based independent simulation program encompassing unit equipment models and exergy analysis models. The program incorporated REFPROP software to accurately calculate fluid physical properties and the heat of conversion between ortho- and parahydrogen. The proposed hydrogen liquefaction process utilized LN precooling, the helium Joule-Brayton cryogenic cycle, and a throttle valve to efficiently produce liquid hydrogen.

Designed Fabrication of SnO/InO/C Electrochemical Sensors for Coolant Leakage Detection in Energy Storage Systems.

The liquid cooling system for lithium iron phosphate battery modules usually faces the threat of coolant leakage, which would dramatically affect the heat transfer performance, safety, and efficiency of the energy storage system. Herein, electrochemical sensing technology has been first employed to detect coolant leakage. Specifically, ethanol is selected as the additive reagent and used as the main tested substance, and the sensors indirectly identify the coolant leakage by detecting the leaked ethanol.

Characterization of the Multiscale Evolution of Coal Pore Structure Under Liquid CO Phase Change Fracturing.

As a green and highly efficient coal seam penetration enhancement technology, liquid CO phase change fracturing (LCPCF) technology has a great deal of promise to advance gas extraction and CO geological storage. A series of investigations were conducted using low-temperature liquid N adsorption (LT-N) adsorption, CO adsorption, CT scanning, and mercury intrusion porosimetry (MIP) to elucidate further the effect of LCPCF on the coal's pore structure. These experiments aimed to characterize coal's internal pore structure parameters and investigate 3D pore structure changes before and after LCPCF treatment at varying fracturing displacements.

Mixture Effects of Polystyrene Microplastics on the Gut Microbiota in C57BL/6 Mice.

Microplastics are plastic particles with sizes of less than 5 mm. The ubiquity of microplastics in the environment has raised serious public health concerns. Microplastics could disturb the composition of the gut microbiota due to both chemical composition and physical interactions, which might further influence the metabolism and immune function of the host.

Insight into the Nature of Nickel Active Sites on the NiAlO Catalyst for Phenanthrene Hydrogenation Saturation.

Hydrogenation saturation of phenanthrene (a typical component of coal tar) could not only improve the combustion performance of fuel oil, but also obtain the raw material for preparing high-energy-density fuel. Nickel-based catalysts have been considered promising catalysts for the hydrogenation saturation of phenanthrene due to their appealing capacity to activate phenanthrene molecules. However, the Ni derivation precursor greatly affects its hydrogenation activity.

Reduced glutathione enhances adipose tissue-derived mesenchymal stem cell engraftment efficiency for liver fibrosis by targeting TGFβ1/SMAD3/NOX4 pathway.

Reduced glutathione (GSH) could reduce oxidative stress to improve adipose tissue-derived mesenchymal stem cell (ADSC) engraftment efficiency in vivo. However, the underlying mechanisms remain unclear. Our goal is to investigate whether GSH enhances ADSC engraftment through targeting the TGFβ/SMAD3/NOX4 pathway.

Facile minocycline deployment in gingiva using a dissolvable microneedle patch for the adjunctive treatment of periodontal disease.

Minocycline is a commonly used drug for adjunctive therapy in periodontal disease. However, the current mainstream local medications primarily rely on intra-pocket administration, which, while avoiding the side effects of traditional systemic drugs, presents challenges such as inconvenience, discomfort, and the need for professional assistance, thus affecting patient compliance. Herein, we introduce a minocycline-loaded dissolvable microneedle (Mino-DMN) patch that allows for local and efficient delivery of minocycline to gingiva for the treatment of periodontitis.

Wearable photobiomodulation halts thyroid cancer growth by leveraging thyroid photosensitivity.

With papillary thyroid carcinoma (PTC) rates rising significantly, concerns about conventional treatments like thyroidectomy and radiotherapy highlight the need for non-invasive options. Our study explores photobiomodulation therapy (PBMT), which uses specific light wavelengths to evoke cellular responses in PTC treatment. Our research utilized a custom-designed optical system to investigate PBMT, finding that blue light at a wavelength of 465 nm can safely and effectively inhibit the proliferation of the TPC-1 PTC cell line by inducing cell cycle arrest.

The Ecological Restoration Strategies in Terrestrial Ecosystems Were Reviewed: A New Trend Based on Soil Microbiomics.

Soil microorganisms play a pivotal role in the biogeochemical cycle and serve as crucial indicators of ecological restoration in terrestrial ecosystems. The soil microbial community is regarded as a pivotal participant in environmental processes, offering both positive and negative feedback to diverse media within the ecosystem. This community can serve as a potential indicator in ecological monitoring and restoration processes.

Survival Benefits of Transarterial Chemoembolization Plus Ablation Therapy in Patients With Intermediate or Advanced Hepatocellular Carcinoma: A Propensity Score Matching Study.

Purpose: To evaluate the survival outcomes of patients with intermediate to advanced hepatocellular carcinoma (HCC), patients who underwent transarterial chemoembolization (TACE) alone were compared with those who underwent a combination of TACE and ablation therapy.

Patients And Methods: This study retrospectively evaluated 536 HCC patients in our hospital from July 2016 to November 2022. All patients underwent TACE, with a subset also receiving ablation therapy.

High-Resolution Proteomics Unveils Salivary Gland Disruption and Saliva-Hemolymph Protein Exchange in -Infected Mosquitoes.

sporozoites, the stage that initiates a malaria infection, must invade the mosquito salivary glands (SGs) before transmitting to a vertebrate host. However, the effects of sporozoite invasion on salivary gland physiology and saliva composition remain largely unexplored. We examined the impact of infection on salivary glands using high-resolution proteomics, gene expression, and morphological analysis.