Effects and Mechanism of lncRNA CRNDE on Sepsis-Induced Acute Kidney Injury.

Objective: To investigate the effects of lncRNA CRNDE on sepsis-associated acute kidney injury in the human kidney 2 cell line and explore the potential mechanisms.

Methods: HK-2 cells were treated with lipopolysaccharides to induce injuries. The expression of CRNDE and miR-146a in HK-2 cells were altered by a transient transfection assay.