A diagnostic classification model of college instructors' value beliefs towards open educational resources.

Open educational resources (OER) can be cost-effective alternatives to traditional textbooks for higher education faculty to decrease student spending on textbooks. To further advocate college instructors' use of OER, understanding their value belief towards integrating OER in teaching is necessary but currently absent. This study thus analyzed 513 college instructors' value beliefs about using OER in college teaching by applying a psychometric model known as diagnostic classification models (DCMs).

Development of an enzymatic cascade to systematically utilize lignocellulosic monosaccharide.

Background: The fermentation valorization of two main lignocellulosic monosaccharides, glucose and xylose, is extensively developed; however, it is restricted by limited yield and process complexity. An in vitro enzymatic cascade reaction can be an alternative approach.

Results: In this study, a three-stage, five-enzyme cascade was developed to convert pretreated biomass to valuable chemicals.

Teachers' beliefs and practices of technology integration at a school for students with dyslexia: A mixed methods study.

The amount of technology available in schools has increased steadily over the past two decades, but higher-level uses have not followed, and many teachers continue to struggle integrating technology in their classrooms. The purpose of this study was to describe teachers' beliefs about technology in the classroom and identify whether their beliefs are reflected in practices of integrating technology at a small, private school for students with dyslexia. A convergent mixed methods action research study was conducted to understand how teachers' beliefs may be affecting technology integration at the school.

A multimodal analysis of college students' collaborative problem solving in virtual experimentation activities: a perspective of cognitive load.

Distance education programs have become the preferred option for most higher education institutions to continue teaching during the COVID-19 pandemic, but the effectiveness of some online courses, especially those engineering courses with experimentation activities, remains disputed. The main challenge is fostering collaborative problem solving skills for novice students as online collaboration increases their cognitive load. This research thus tapped into novice engineering students' cognitive load to develop a more granular, multimodal view of how cognitive load influences student performance in collaborative problem solving during virtual experimentation activities.

Improving K-12 Teachers' Acceptance of Open Educational Resources by Open Educational Practices: A Mixed Methods Inquiry.

Teachers in K-12 settings increasingly demand instructional materials beyond textbooks to follow the upward momentum of personalized instruction. Especially during the outbreak of COVID-19, K-12 teachers are forced to quickly adapt to online teaching and thus have more difficulties of delivering personalized instruction in a relatively resource-restraint situation. Open educational resources (OER), allowing teachers to retain, reuse, revise, remix, and redistribute high-quality educational resources at no costs, can be a viable option for teachers.

Enhanced isomerization of rare sugars by ribose-5-phosphate isomerase A from Ochrobactrum sp. CSL1.

Ribose-5-phosphate isomerase A (RpiA) is of great importance in biochemistry research, however its application in biotechnology has not been fully explored. In this study the activity of RpiA from Ochrobactrum sp. CSL1 (OsRpiA) towards D-allose was engineered based on sequential and structural analyses.

Engineering ribose-5-phosphate isomerase B from a central carbon metabolic enzyme to a promising sugar biocatalyst.

Ribose-5-phosphate isomerase B (RpiB) was first identified in the pentose phosphate pathway responsible for the inter-conversion of ribose-5-phosphate and ribulose-5-phosphate. Though there are seldom key enzymes in central carbon metabolic system developed as useful biocatalysts, RpiB with the advantages of wide substrate scope and high stereoselectivity has become a potential biotechnological tool to fulfill the demand of rare sugars currently. In this review, the pivotal roles of RpiB in carbon metabolism are summarized, and their sequence identity and structural similarity are discussed.

Implementing open educational resources in digital education.

The outbreak of COVID-19 leads to an increasing demand for online educational resources to continue teaching and learning. Open educational resources (OER), with the benefits of cost-saving and open licenses, have great potential in facilitating the rapid transition to digital education, but concerns about whether OER decrease the effectiveness of student learning remains unsolved. Hilton's review article (2016) provides synthesized evidence stating that OER can help decrease college students' textbook spending without undermining student learning effectiveness.

Ubiquitin-specific protease 49 attenuates IL-1β-induced rat primary chondrocyte apoptosis by facilitating Axin deubiquitination and subsequent Wnt/β-catenin signaling cascade inhibition.

Osteoarthritis (OA) is an age-related chronic joint degenerative disease. Interleukin 1 beta (IL-1β) is considered a marker for the progression of OA. In this study, we found that Ubiquitin-Specific Peptidase 49 (USP49) was significantly less expressed in OA patients compared with healthy individuals.

Exploring Multifunctional Residues of Ribose-5-phosphate Isomerase B from sp. CSL1 Enhancing Isomerization of d-Allose.

Ribose-5-phosphate isomerase B is of great importance for biocatalysis and biosynthesis, but the multifunctional residues in active sites hinder the research efforts. This study employed rational design strategies to locate the key residues of RpiB from sp. CSL1 (OsRpiB).

DRP5 is involved in cancer cell growth and predicts poor prognosis in human osteosarcoma.

Osteosarcoma is an extremely aggressive primary malignant bone tumor of childhood. Collapsin response mediator proteins (CRMPs), which are highly expressed in the developing nervous system, were recently shown to be associated with cancer development. However, the relationship between DRP5 (CRMP5) and osteosarcoma has not been evaluated.

Arthroscopic repair of the meniscal injury using meniscal repair device.

Background: Total meniscus resection after meniscus tear usually leads to faster degeneration and osteoarthritis of the knee joint. Preservation and repair of the injured menisci are therefore of great clinical importance. The aim of this study was to evaluate the clinical effects of arthroscopic repair of meniscal injuries using the Fast-Fix device.

[Mid-term effectiveness of Oxford Unicompartmental Knee System Phase III for medial unicompartmental knee osteoarthritis].

Objective: To evaluate the mid-term effectiveness of Oxford Unicompartmental Knee system Phase III for medial unicompartmental knee osteoarthritis (OA).

Methods: Between December 2008 and August 2010, 26 patients (32 knees) with medial unicompartmental knee OA were treated. Of 26 patients, 11 were followed up more than 2 years, including 7 males and 4 females (14 knees, 6 left and 8 right knees) with an average age of 62.

[Arthroscopically assisted treatment for acute patellar dislocation].

Objective: To evaluate an improving operative procedure and the clinical results of arthroscopically assisted treatment for acute patellar dislocation.

Methods: Between April 2006 and March 2009, 22 patients (25 knees) with primary acute complete dislocation of the patella underwent an improving arthroscopic operation, release of lateral retinaculum and suture of medial capsule and retinaculum structure. There were 5 males and 17 females with an average age of 23.