Effect of substrate concentration on sulfamethoxazole wastewater treatment by osmotic microbial fuel cell: Insight into operational efficiency, dynamic changes of membrane fouling and microbial response.

To solve the problems of antibiotic pollution, water resources and energy shortage, an osmotic microbial fuel cell (OsMFC) was adopted innovatively to treat antibiotic wastewater containing sulfamethoxazole (SMX), and achieved SMX removal, water production and electricity generation. Substrate concentration was one of the key factors affecting the performances of OsMFC, but there were few relevant studies This study explored the effect of substrate concentration on system performances, clarified the dynamic changes of membrane fouling under different substrate concentrations, and further revealed the response of microbial communities. The results showed that the stable removal efficiency of SMX exceeded 98.

Oxidative stress initiates hemodynamic change in CKD-induced heart disease.

Chronic kidney disease (CKD) predisposes to cardiac remodeling and coronary microvascular dysfunction. Studies in swine identified changes in microvascular structure and function, as well as changes in mitochondrial structure and oxidative stress. However, CKD was combined with metabolic derangement, thereby obscuring the contribution of CKD alone.

Effect of Mn on RO membrane organic fouling: Insights into the complexation and interfacial interaction.

RO process is commonly used to treat and reuse manganese-containing industrial wastewater. Nevertheless, even after undergoing multi-stage treatment, the secondary biochemical effluent still exhibits a high concentration of Mn coupled with organics entering the RO system, leading to membrane fouling. In this work, we systematically analyze the RO membrane organic fouling processes and mechanisms, considering the coexistence of Mn with humic acid (HA), sodium alginate (SA), bovine serum albumin (BSA) and their mixtures (HBS).

Retinoic acid modulation guides human-induced pluripotent stem cell differentiation towards left or right ventricle-like cardiomyocytes.

Background: Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) by traditional methods are a mix of atrial and ventricular CMs and many other non-cardiomyocyte cells. Retinoic acid (RA) plays an important role in regulation of the spatiotemporal development of the embryonic heart.

Methods: CMs were derived from hiPSC (hi-PCS-CM) using different concentrations of RA (Control without RA, LRA with 0.

Critical review on salt tolerance improvement and salt accumulation inhibition strategies of osmotic membrane bioreactors.

The osmotic membrane bioreactor (OMBR) is a novel wastewater treatment and resource recovery technology combining forward osmosis (FO) and membrane bioreactor. It has attracted attention for its low energy consumption and high contaminant removal performance. However, in the long-term operation, OMBR faces the problem of salt accumulation due to high salt rejection and reverse salt flux, which affects microbial activity and contaminants removal efficiency.

Predictors of gastrointestinal bleeding in patients with acute coronary syndrome and the optimal duration of dual antiplatelet therapy.

Background: This study aims to estimate the risk factors of gastrointestinal (GI) bleeding in patients with acute coronary syndrome (ACS) and to evaluate the optimal duration of dual antiplatelet therapy (DAPT).

Materials And Methods: We enrolled 1266 patients with ACS in a telephone follow-up program to determine whether any of the patients were hospitalized for GI bleeding. We collected baseline data, laboratory tests, electrocardiograms, and echocardiography covering all ACS patients.

Research on the Application and Mechanisms of Electroactive Microorganisms in Toxicants Monitoring: A Review.

A biological treatment is the core process for removing organic pollutants from industrial wastewater. However, industrial wastewater often contains large amounts of toxic and harmful pollutants, which can inhibit the activity of microorganisms in a treatment system, precipitate the deterioration of effluent quality, and threaten water ecological security from time to time. In most of the existing anaerobic biological treatment processes, toxic effects on microorganisms are determined according to the amounts of end-products of the biochemical reactions, and the evaluation results are relatively lacking.

Simultaneous Wastewater Treatment and Resources Recovery by Forward Osmosis Coupled with Microbial Fuel Cell: A Review.

Osmotic microbial fuel cells (OsMFCs) with the abilities to simultaneously treat wastewater, produce clean water, and electricity provided a novel approach for the application of microbial fuel cell (MFC) and forward osmosis (FO). This synergistic merging of functions significantly improved the performances of OsMFCs. Nonetheless, despite their promising potential, OsMFCs currently receive inadequate attention in wastewater treatment, water reclamation, and energy recovery.

A Comprehensive Analysis of the Impact of Inorganic Matter on Membrane Organic Fouling: A Mini Review.

Membrane fouling is a non-negligible issue affecting the performance of membrane systems. Particularly, organic fouling is the most persistent and severe form of fouling. The complexation between inorganic and organic matter may exacerbate membrane organic fouling.

Differences in the Effect of Mn on the Reverse Osmosis Membrane Fouling Caused by Different Types of Organic Matter: Experimental and Density Functional Theory Evidence.

Landfill leachate from some sites contains a high concentration of Mn, which may cause reverse osmosis (RO) membrane fouling during RO treatment. In this study, the effect of Mn on RO membrane fouling caused by typical organic pollutants (humic acid (HA), protein (BSA), and sodium alginate (SA)) was systematically investigated, and it was found that Mn exacerbates RO membrane fouling caused by HA, SA, and HBS (mixture of HA + BSA + SA). When the Mn concentration was 0.

Predicting protective gene biomarker of acute coronary syndrome by the circRNA-associated competitive endogenous RNA regulatory network.

The mortality and disability rates of acute coronary syndrome (ACS) are quite high. Circular RNA (circRNA) is a competitive endogenous RNA (ceRNA) that plays an important role in the pathophysiology of ACS. Our goal is to screen circRNA-associated ceRNA networks for biomarker genes that are conducive to the diagnosis or exclusion of ACS, and better understand the pathology of the disease through the analysis of immune cells.

FGFR4 promotes nuclear localization of GABP to inhibit cell apoptosis in uterine leiomyosarcoma.

Fibroblast growth factor receptor 4 (FGFR4) has been indicated as a potential "oncogene" in various types of cancer. However, the effects and underlying mechanisms of FGFR4 on uterine leiomyosarcoma (ULMS) progression remain unclear. In this study, we firstly discovered that FGFR4 was upregulated in ULMS specimens and cell lines and closely associated with poor prognosis of ULMS patients.

Prognostic indicators of new onset atrial fibrillation in patients with acute coronary syndrome.

Background: This study aims to estimate prognostic indicators of new onset atrial fibrillation (AF) in patients with acute coronary syndrome (ACS) through 3 to 5 years of follow-up.

Hypothesis: For patients with ACS, some prognostic indicators can be used to predict new onset AF.

Methods: The Improving Care for Cardiovascular Disease in China-ACS (CCC-ACS) program was launched in 2014 by a collaborative initiative of the American Heart Association and Chinese Society of Cardiology.

Activity profiles of full-match and substitution players in the 2018 FIFA World Cup.

In order to better understand the intensity of match activities of full-match and substitution football players, running performance of 527 players who generated 1167 match observations in the 2018 FIFA World Cup were analysed. Differences in activity profiles between groups (1st and 2nd half full-match, early and late substitutes) were quantified by the generalised mixed linear modelling. Results showed that: (1) Full-match players presented trivial changes (ES: 0.

Technical and physical match performance of teams in the 2018 FIFA World Cup: Effects of two different playing styles.

In order to investigate the effect of playing styles on the match performance of football teams, data were analysed on 18 technical performance-related variables and 8 physical performance-related variables from 59 matches in the 2018 FIFA World Cup. A -means cluster analysis was conducted to classify all match observations into two clusters of tactical approach in order to identify the playing styles of teams (characterised as direct-play, possession-play and mixed-play). Separate Poisson regression models were run in the generalised mixed linear modelling to examine the differences in technical and physical performance between teams classified as using different playing styles when facing different opponents.

Running Performance of Soccer Players During Matches in the 2018 FIFA World Cup: Differences Among Confederations.

With the purpose of quantifying the differences in the running performance of soccer players during matches from different continental confederations, data of 1508 match observations generated from 559 players in 59 matches at the 2018 FIFA World Cup held in Russia were analyzed. Generalized mixed linear modeling was carried out to estimate the effect of confederations on each of the selected thirteen match running performance related variables (total distance covered, top speed achieved, number of sprints, distance covered and time spent in walking, jogging, low-speed running, moderate-speed running, and high-speed running), controlling the effects of match result, competition phase, and team and opponent strength. Results showed that the differences in the match running performance of UEFA and CONMEBOL players were trivial (ES between 0.

Tripartite Motif-Containing Protein 59 (TRIM59) Promotes Epithelial Ovarian Cancer Progression via the Focal Adhesion Kinase(FAK)/AKT/Matrix Metalloproteinase (MMP) Pathway.

BACKGROUND The tripartite motif-containing protein 59 (TRIM59) is an important member of the TRIM family, which regulates biological processes. However, the relationship between TRIM59 and epithelial ovarian cancer (EOC) is not clear. MATERIAL AND METHODS The TRIM59 expression level was detected in EOC tissues and cell lines.

Effect of ticagrelor versus prasugrel on platelet reactivity: a meta-analysis.

Background And Objective: Whether ticagrelor is superior to prasugrel in inhibiting platelet reactivity (PR) has remained unclear, possibly because different test methods have been used to determine this. Therefore, using a different test method, we performed a meta-analysis comparing the effects of ticagrelor and prasugrel on PR.

Methods And Results: PubMed, Embase, Web of Science, and Google Scholar were searched - without language restrictions (last updated on 26 February 2017) - for randomized trials comparing the effects of prasugrel with those of ticagrelor in patients with coronary artery disease.

Effects of erythropoiesis-stimulating agents on heart failure patients with anemia: a meta-analysis.

Introduction: Heart failure (HF) is always complicated with anemia and is associated with bad prognosis in this patient population. Several studies have assessed the potential role of erythropoietin-stimulating agent (ESA) in improving cardiac function and reducing the number of hospitalizations in anemic patients with HF.

Aim: We performed a meta-analysis to assess the potential role of ESA in the treatment of anemic patients with HF.

Mean platelet volume on admission improves risk prediction in patients with acute coronary syndromes.

Our aim was to evaluate the incremental predictive value of adding mean platelet volume (MPV) to the Global Registry of Acute Coronary Events (GRACE) risk score. The MPV and GRACE score were determined on admission in 509 consecutive patients with acute coronary syndrome (ACS). Six-month mortality or nonfatal myocardial infarction (MI) was the study end point.