Disassortative Network Structure Improves the Synchronization between Neurons in the Suprachiasmatic Nucleus.

In mammals, an endogenous clock located in the suprachiasmatic nucleus (SCN) of the brain regulates the circadian rhythms of physiological and behavioral activities. The SCN is composed of about 20,000 neurons that are autonomous oscillators with nonidentical intrinsic periods ranging from 22 h to 28 h. These neurons are coupled through neurotransmitters and synchronized to form a network, which produces a robust circadian rhythm of a uniform period.

A Patient Suffering From Neurodegenerative Disease May Have a Strengthened Fractal Gait Rhythm.

Scale invariance in stride series, namely, the series shows similar patterns across multiple time scales, is used widely as a non-invasive identifier of health assessment. Detailed calculations in the literature with standard tools, such as de-trended fluctuation analysis and wavelet transform modulus maxima seem to lead a conclusion that patients suffering from neurodegenerative diseases have weakened fractal gait rhythm compared with healthy persons. These variance-based methods are dynamical mechanism dependent, namely, for some dynamical process the scale invariance cannot be detected qualitatively, while for some others the scale invariance can be detected correctly, but the estimated value of scaling exponent is not correct.