Publications by authors named "Hengfei Cui"

Accurate myocardial segmentation is crucial in the diagnosis and treatment of myocardial infarction (MI), especially in Late Gadolinium Enhancement (LGE) cardiac magnetic resonance (CMR) images, where the infarcted myocardium exhibits a greater brightness. However, segmentation annotations for LGE images are usually not available. Although knowledge gained from CMR images of other modalities with ample annotations, such as balanced-Steady State Free Precession (bSSFP), can be transferred to the LGE images, the difference in image distribution between the two modalities (i.

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Background: The prognostic value of left ventricular (LV) myocardial trabecular complexity on cardiovascular magnetic resonance (CMR) in dilated cardiomyopathy (DCM) remains unknown. This study aimed to evaluate the prognostic value of LV myocardial trabecular complexity using fractal analysis in patients with DCM.

Methods: Consecutive patients with DCM who underwent CMR between March 2017 and November 2021 at two hospitals were prospectively enrolled.

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Chest radiography is the most common radiology examination for thoracic disease diagnosis, such as pneumonia. A tremendous number of chest X-rays prompt data-driven deep learning models in constructing computer-aided diagnosis systems for thoracic diseases. However, in realistic radiology practice, a deep learning-based model often suffers from performance degradation when trained on data with noisy labels possibly caused by different types of annotation biases.

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Deformable medical image registration can achieve fast and accurate alignment between two images, enabling medical professionals to analyze images of different subjects in a unified anatomical space. As such, it plays an important role in many medical image studies. Current deep learning (DL)-based approaches for image registration directly learn spatial transformation from one image to another, relying on a convolutional neural network and ground truth or similarity metrics.

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Detailed information of substructures of the whole heart is usually vital in the diagnosis of cardiovascular diseases and in 3D modeling of the heart. Deep convolutional neural networks have been demonstrated to achieve state-of-the-art performance in 3D cardiac structures segmentation. However, when dealing with high-resolution 3D data, current methods employing tiling strategies usually degrade segmentation performances due to GPU memory constraints.

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Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) provides metabolic information, while Computed Tomography (CT) provides the anatomical context of the tumors. Combined PET-CT segmentation helps in computer-assisted tumor diagnosis, staging, and treatment planning. Current state-of-the-art models mainly rely on early or late fusion techniques.

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Background: Myocardial pathology segmentation plays an utmost role in the diagnosis and treatment of myocardial infarction (MI). However, manual segmentation is time-consuming and labor-intensive, and requires a lot of professional knowledge and clinical experience.

Methods: In this work, we develop an automatic and accurate coarse-to-fine myocardial pathology segmentation framework based on the U-Net++ and EfficientSeg model.

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Background: A novel Generative Adversarial Networks (GAN) based bidirectional cross-modality unsupervised domain adaptation (GBCUDA) framework is developed for cardiac image segmentation, which can effectively tackle the problem of network's segmentation performance degradation when adapting to the target domain without ground truth labels.

Method: GBCUDA uses GAN for image alignment, applies adversarial learning to extract image features, and gradually enhances the domain invariance of extracted features. The shared encoder performs an end-to-end learning task in which features that differ between the two domains complement each other.

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Accurate and automatic segmentation of the hippocampus plays a vital role in the diagnosis and treatment of nervous system diseases. However, due to the anatomical variability of different subjects, the registered atlas images are not always perfectly aligned with the target image. This makes the segmentation of the hippocampus still face great challenges.

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Background And Objective: Automatic cardiac segmentation plays an utmost role in the diagnosis and quantification of cardiovascular diseases.

Methods: This paper proposes a new cardiac segmentation method in short-axis Magnetic Resonance Imaging (MRI) images, called attention U-Net architecture with input image pyramid and deep supervised output layers (AID), which can fully-automatically learn to pay attention to target structures of various sizes and shapes. During each training process, the model continues to learn how to emphasize the desired features and suppress irrelevant areas in the original images, effectively improving the accuracy of cardiac segmentation.

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Intravascular ultrasound (IVUS) has been widely used to capture cross sectional lumen frames of inner wall of coronary arteries. This kind of medical imaging modalities is capable of providing detailed and significant information of lumen contour shape, which is very important for clinical diagnosis and analysis of cardiovascular diseases. Numerous learning based techniques have recently become very popular for coronary artery segmentation due to their impressive results.

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The CT angiography (CTA) is a clinically indicated test for the assessment of coronary luminal stenosis that requires centerline extractions. There is currently no centerline extraction algorithm that is automatic, real-time and very accurate. Therefore, we sought to (i) develop a hybrid approach by incorporating fast marching and Runge-Kutta based methods for the extraction of coronary artery centerlines from CTA; (ii) evaluate the accuracy of the present method compared to Van's method by using ground truth centerline as a reference; (iii) evaluate the coronary lumen area of our centerline method in comparison with the intravascular ultrasound (IVUS) as the standard of reference.

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