Publications by authors named "Hengameh Nazari"

Article Synopsis
  • Crohn's disease perianal fistulae often don't respond well to standard therapies, but mesenchymal stem cell (MSC)-derived exosomes have shown potential as a treatment, being deemed safe in previous studies.
  • A phase II clinical trial was conducted with 23 patients suffering from refractory perianal fistulas, where exosomes were injected directly into the fistula tracts over a period of 6 months.
  • Results indicated that 60% of patients achieved complete fistula closure, and overall, 69.7% of treated fistula tracts showed significant closure, along with some observed improvements in discharge from the tracts.
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Background: The aim of this study was to determine whether mammographic and sonographic features of malignant breast lesions are correlated with tumor histologic grade, hormonal receptor, human epidermal growth factor receptor 2 (HER2), and Ki-67 status.

Materials And Methods: In this retrospective study, imaging and histopathological findings of 187 biopsy-proven breast cancer cases from November 2019 to February 2021 were reviewed. The Chi-square test was used to examine the potential correlation between mammographic and sonographic characteristics with histopathological features such as hormonal receptor, HER2 status, Ki-67 labeling index, and histological grade.

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Background: Primary cardiac myxofibrosarcoma is a rare and aggressive malignancy, with the majority of approaching strategies relying on case reports. This article provides insights into its diagnosis and treatment.

Case Presentation: This paper presents the case of a 40-year-old man with sudden onset hemoptysis, leading to the diagnosis of primary cardiac myxofibrosarcoma.

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Accurate detection of respiratory system damage including COVID-19 is considered one of the crucial applications of deep learning (DL) models using CT images. However, the main shortcoming of the published works has been unreliable reported accuracy and the lack of repeatability with new datasets, mainly due to slice-wise splits of the data, creating dependency between training and test sets due to shared data across the sets. We introduce a new dataset of CT images (ISFCT Dataset) with labels indicating the subject-wise split to train and test our DL algorithms in an unbiased manner.

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Article Synopsis
  • * Eleven patients with long-term fistulas received exosome injections, and after six months, most showed improvement, with several achieving complete resolution of their condition.
  • * The findings suggest that MSC-derived exosomes are safe and effective in treating complex perianal fistulas, highlighting their potential for future research and clinical use.
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