Histological and mechanical properties of autologous living tissue biotubes.

The aim of this study was to explore and evaluate biotubes consisting of autologous tissues. The biotubes were prepared by intra-abdominally embedding silicon rods as moulds. The specimens were analyzed by mechanical tests, histological observation and superficial study.

[Outcome comparison of open versus endovascular techniques in the treatment of abdominal aortic aneurysms].

Objective: To compare the efficacy, cost and safety of endovascular aortic repair (EVAR) versus open surgery in the treatment of infrarenal abdominal aortic aneurysms.

Methods: Retrospective analyses were conducted for the clinical data and follow-up information of 218 cases from January 2002 to December 2011 at our hospital. Open surgery group included 86 patients with an mean age of 65.

[Management strategies of arterial prosthetic graft infection in lower extremity:a report of 5 cases].

Objective: To explore the management strategies of pyogenic vascular prosthetic graft infection.

Methods: The clinical data of 5 cases of prosthetic vascular graft infection in lower extremity between 2003 and 2010 were retrospectively analyzed.

Results: All of them were treated by antibiotics, debridement and drainage.

[Efficacies of carotid endarterectomy in the treatment of atherosclerotic carotid artery stenosis].

Objective: To explore the feasibility and efficacy of carotid endarterectomy (CEA) in the treatment of atherosclerotic carotid artery stenosis (ACAS).

Methods: From January 2002 to December 2010, 126 ACAS patients undergoing carotid endarterectomy at our hospital were retrospectively analyzed. There were 92 males and 34 females with an average age of 65.

Mesocavoatrial shunt for Budd-Chiari syndrome: a case report with long-term follow-up.

Background: A case of mesocavoatrial shunting for the treatment of Budd-Chiari syndrome (BCS) with long-term follow-up is reported.

Methods: A 25-year-old man with stage II BCS was treated with a mesocavoatrial shunt to decompress the portal and IVC hypertension. During the 6-year follow-up, the patient was able to resume work as a salesperson and has since led a normal life.

[Genetic analysis in the clinical diagnosis of Ehlers-Danlos syndrome type IV].

Objective: To ascertain the diagnosis of such a rare disease as Ehlers-Danlos syndrome type IV by the technique of DNA(deoxyribonucleic acid)analysis.

Methods: The primer sequences of Col3A1 gene were designed. Genomic DNA was isolated from the peripheral blood samples.

A new self-convertible inferior vena cava filter: experimental in-vitro and in-vivo evaluation.

Purpose: To evaluate using in-vitro and in-vivo models the feasibility and capture efficiency of a new self-convertible inferior vena cava filter (SCF), equipped with a biodegradable self-converting switch.

Materials And Methods: Capture rates were tested in an in-vitro flow model for simulated supine and upright positions with clot diameters of 3 mm and 5 mm and tube diameters of 22 mm, 25 mm, and 28 mm. In the in-vivo study, five filters were implanted in five adult dogs.

Mesojugular shunt for Budd-Chiari syndrome: a case report with long-term follow-up.

Background: We report a case of a mesojugular shunt for Budd-Chiari syndrome (BCS) with long-term follow-up.

Methods: A 32-year-old woman presented with late stage BCS. She was treated with a mesojugular shunt to relieve her portal hypertension.

[Preliminary evaluation of clinical effects of below-knee arterial bypass on diabetic lower limb ischemia].

Objective: To evaluate medium-long term patency of below-knee bypass on patients who suffered from diabetic lower limb ischemia.

Methods: Clinical and follow-up data of 51 patients was retrospectively analyzed who underwent 56 below-knee bypass because of diabetes from November 2001 to December 2006. There were 35 male and 16 female with an average age of 68 years.

[Treatment of severe acute deep venous thrombosis in lower extremity].

Objective: To explore the method and effectiveness of treatment for severe acute deep venous thrombosis (DVT) in lower extremity.

Methods: Eighteen patients with severe acute DVT treated in our hospital from January 1, 2002 to December 31, 2008 were retrospectively analysed. All the patients had limb edema and pain, sixteen had limb cyanochroia(one had calf skin ulcer and foot gangrene), two had limb pallor, ten had weakened dorsalis pedis artery pulsation, eight had silent dorsalis pedis artery pulsation.

Management of complex patients with Budd-Chiari syndrome.

Therapy for patients with Budd-Chiari syndrome is well established. For those with commonly seen localized lesions, percutaneous transluminal angioplasty or stenting is the first-line treatment. Treatment methods for severely ill patients in whom intervention has failed, or those in a poor general condition, are worth exploring.

Aortobilateral axillary bypass to treat severe cerebral ischemia due to Takayasu's arteritis.

Cerebral ischemia resulting from four cervical arterial occlusions due to Takayasu's arteritis is a rare condition. Ascending aortounilateral/-bilateral internal carotid arterial bypass is a means for relieving it. However, postoperative reperfusion syndrome remains an unsolved severe, even fatal complication.

[Treatment of severe cerebral ischemia in Takayasu's disease with arterial reconstruction].

Objective: To evaluate the effect of surgical bypass and to explore the role of transcranial doppler (TCD) during the bypass operation.

Methods: From March 2003 to February 2008, sixteen patients (4 male and 12 female) with mean age of 32 years old and mean disease course of 7.5 years were treated by surgical procedures.

[Management of difficult, severe and recurrent Budd-Chiari syndrome].

Objective: To investigate the management of complicated, severe or recurrent Budd-Chiari syndrome.

Methods: From February 2004 to August 2007, 28 patients with complicated, severe or recurrent Budd-Chiari syndrome were treated. In this series, 16 patients relapsed after treated with percutaneous transluminal angioplasty or stent deployment, 2 cases relapsed after surgery; and the other 10 were under severe conditions and hard to treat, including malignancy of the inferior vena cava and right atrium.

Transplantation of autologous bone marrow mononuclear cells for patients with lower limb ischemia.

Background: Many treatment options for lower limb ischemia are difficult to apply for the patients with poor arterial outflow or with poor general conditions. The effect of medical treatment alone is far from ideal, especially in patients with diabetic foot. A high level amputation is inevitable in these patients.

[Preliminary in vivo evaluation of tissue engineered venous grafts fabricated based on endothelial progenitor cells].

Objective: To explore the feasibility of the tissue engineered venous grafts (TEVGs) constructed in vitro based on canine autologous bone marrow-derived endothelial progenitor cells (EPCs) and porcine decellularized aortic scaffolds implanted into the canine inferior vena cava.

Methods: To draw out a volume of 8 - 12 ml of bone marrow from the canine (n = 8), to culture and expand EPCs in vitro using conditioned medium. After labeled with a red fluorescent dye PKH26-GL, the cells were seeded onto the luminal surface of decellularized porcine scaffolds with single, rotative method for 4 h.

[Clinical analysis of vascular reconstruction in 56 cases of lower extremity ischemia suffering from infrapopliteal arterial occlusion].

Objective: To summarize therapeutic efficacy of vascular reconstruction in treating infrapopliteal arterial occlusion.

Methods: Retrospective analysis of vascular reconstruction of lower extremity was made in 56 cases suffering from popliteal arteries or 3 branches of popliteal arteries (anterior tibial, posterior tibial, peroneal artery) between July 2001 and August 2005 in our hospital. According to the level of lower extremity arterial occlusion, a composite grafts which consisting of a combined proximal PTFE prosthesis grafts with autogenous vein grafts were used to establish the sequential vascular reconstruction for multilevel and multistage arterial occlusive disease.

Surgical treatment of 82 patients with diabetic lower limb ischemia by distal arterial bypass.

Background: Diabetic lower limb ischemia is a serious complication of diabetes mellitus. This study was conducted to investigate the effectiveness of distal arterial bypass treatment in diabetic patients with lower limb ischemia.

Methods: From July 2000 to July 2004, 96 lower limbs of 82 diabetic patients (type 2) with severe lower limb ischemia were treated in Xuan Wu Hospital.

[Challenges in management of cerebral ischemia due to Takayasu's arteritis].

Objective: To explore the management of cerebral ischemia caused by Takayasu's arteritis.

Methods: One hundred and three cases treated from 1984 to 2003 were reviewed including 92 females. Seven cases underwent ascending aorta to bilateral internal carotid artery (ICA) bypass, 38 cases to the axillary artery with graft to single ICA bypass.

[Primary experimental study on the construction of tissue engineering blood vessel].

Objective: To explore the primary experimental methods to construct tissue engineering blood vessel.

Methods: Using the collagen-chitosan to prefabricate the scaffolds with 3-dimensional structure, the proliferated human endothelial cells (ECs), smooth muscle cells (SMCs) and fibroblasts act as the seed cells. The cells were seeded to scaffolds in two-step method, and engineering tissue were matured by static culture or bioreactor culture.