Publications by authors named "Hendrik Lesch"
Article Synopsis
- Atrial fibrillation (AF) significantly increases the risk of stroke, and identifying risk factors for strokes in AF patients remains complicated, suggesting that existing scoring systems don't capture all relevant details.
- In a study analyzing patients from the ARENA project, it was found that those with a history of cerebrovascular events (CVE) were generally older, had higher CHADS-VASc scores, and larger left atrial diameters compared to those without CVE.
- The prognosis for AF patients with CVE was notably worse; they had higher mortality rates and higher stroke occurrences within a year, indicating that factors like atrial remodeling and underlying heart disease may contribute to their increased risk.
Introduction: Neurocritical care patients with neurovascular disease often face poor long-term outcomes, highlighting the pivotal role of evidence-based interventions. Although International Guidelines emphasize managing basic physiological parameters like temperature, blood glucose, blood pressure, and oxygen levels, physician adherence to these targets remains uncertain. This study aimed to assess adherence to guideline-based treatment targets for basic physiological parameters in neurocritical care.
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- * Collaboration between cardiologists and neurologists is essential since the causes for elevated hs-cTn can be diverse, sometimes presenting atypically or silently, and some may be life-threatening, such as myocardial infarction.
- * The majority of hs-cTn increases in AIS patients result from non-ischemic myocardial injury, and the paper provides an updated clinical algorithm to assist in differential diagnosis for these cases.
Background And Aims: Left atrial (LA) enlargement has been repeatedly shown to be associated with the diagnosis of atrial fibrillation (AF). In clinical practice, several parameters are available to determine LA enlargement: LA diameter index (LADI), LA area index (LAAI), or LA volume index (LAVI). We investigated the predictive power of these individual LA parameters for AF in patients with acute ischemic stroke or transient ischemic attack (TIA).
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- Primary familial brain calcification (PFBC) and early-onset Alzheimer's disease (EOAD) may have shared genetic causes, as seen in a patient with both conditions.
- A specific mutation in the SLC20A2 gene was linked to brain calcifications, while another mutation in the PSEN1 gene was connected to early-onset dementia symptoms.
- The study suggests that the effects of these two genetic mutations appear to add to each other rather than interact in a more complex way, and emphasizes the importance of neuropsychological assessments and amyloid PET scans for diagnosing these disorders.
Functional dissociation of multiple-object tracking mechanisms based on hemispheric asymmetries.
Restor Neurol Neurosci
October 2021
Background: A number of theoretical accounts have been put forward to explain the ability to simultaneously track multiple visually indistinguishable objects over a period of time. Serial processing models of visual tracking focus on the maintenance of the spatial locations of every single item over time. A more recent mechanism describes multiple object tracking as the ability to maintain a higher order representation of an abstract spatial configuration built by the illusory connection of the tracked items through their transition.
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