Publications by authors named "Hend Al-Wathnani"

Article Synopsis
  • Bioremediation of Cd (cadmium) contaminated environments can be enhanced by using plant-growth-promoting bacteria (PGPB), such as Burkholderia contaminans ZCC, which was isolated from mining soil and shows high resistance to cadmium.
  • The genomic analysis revealed that B. contaminans ZCC has unique heavy metal resistance traits due to the presence of specific genes on plasmids, allowing it to tolerate cadmium and other metals more effectively than other strains.
  • Additionally, B. contaminans ZCC displays beneficial traits for plant growth, like promoting root development and nutrient availability, and can help soybean plants grow in soils with high cadmium levels, making it a potential tool for bioremediation efforts.
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Heavy metals (HMs) are compounds that can be hazardous and impair growth of living organisms. Bacteria have evolved the capability not only to cope with heavy metals but also to detoxify polluted environments. Three heavy metal-resistant strains of and one of were isolated from the gold/copper Zijin mining site, Longyan, Fujian, China.

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In this study, HepG2 cells were exposed to 6-hydroxy- 2,2',4,4'-tetrabromodiphenyl ether (6-OH-BDE-47) for 3 and 6 days for monitoring cytotoxic effects and alterations in its transcriptomic profile. MTT assay showed that cells exposed to 6-OH-BDE-47 (50 nM) exhibited 48.5% and 53.

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We have evaluated the in vitro low dose hepatotoxic effects of two flame-retardants (BDE-47 and BDE-32) in HepG2 cells. Both congeners declined the viability of cells in MTT and NRU cell viability assays. Higher level of intracellular reactive oxygen species (ROS) and dysfunction of mitochondrial membrane potential (ΔΨm) were observed in the treated cells.

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