Technology use in long-term care during the COVID-19 pandemic: A qualitative study of paid employees' experiences in Western Canada.

Background: During the COVID-19 pandemic, governments across the world implemented processes and policies to limit the spread of COVID-19, especially in long-term care (LTC) homes. This led to changes in technology use for persons living in LTC homes, their families and friends, as well as the paid workforce dedicated to caring for them.

Objective: The study describes the role of technology and its impact on the experiences of LTC staff working in northern and rural areas in Western Canada during COVID-19.

Use of Antivibration Technology to Reduce Demands for In-Home Nursing Care and Support in Rural Settings for Persons with Essential Tremors: A Qualitative Study.

Introduction: With the increased integration of technologies in the healthcare sector, it is important to understand the benefits emerging technologies may play to reduce demands on the health care system. The Steadiwear antivibration glove shows promise for enhancing the independence in functional abilities for persons with essential tremors and for alleviating the need for support from the health care system. The objective of this study was to examine Registered Nurses' (RN) perceptions of the potential for the Steadiwear antivibration glove to reduce the need for in-person support from community healthcare workers.

Monitoring and Evaluation of Dementia-Friendly Neighborhoods Using a Walkshed Approach: Protocol for a Scoping Review.

Background: The number of people in society living with dementia is growing. In Canada, most people who live with dementia live at home, often in a neighborhood setting. Neighborhood environments can be a source of independence, social engagement, and well-being.

Impacts of Technology Use on the Workload of Registered Nurses: A Scoping Review.

Introduction: Technology is an integral part of healthcare. With the rapid development of technological innovations that inform and support nurses, it is important to assess how these technologies may affect their workload particularly in rural contexts, where the workforce and supports may be limited.

Methods: This literature review guided by Arksey and O'Malley's scoping review framework describes the breadth of technologies which impact on nurses' workload.

Timing of oceans on Mars from shoreline deformation.

Widespread evidence points to the existence of an ancient Martian ocean. Most compelling are the putative ancient shorelines in the northern plains. However, these shorelines fail to follow an equipotential surface, and this has been used to challenge the notion that they formed via an early ocean and hence to question the existence of such an ocean.

Analysis of outcomes achieved with squamous cell carcinomas of the anus in a single university hospital over the last two decades: Clinical response rate, relapse and survival of 190 patients.

Background And Objectives: We reviewed our series of anal squamous cell carcinomas (ASCC) treated over the last two decades.

Methods: ASCC patients undergoing treatment at the Leicester Royal Infirmary between 1998 and 2016 were selected. Age, gender, pathological tumor characteristics, treatment adopted, the overall survival (OS), cancer-specific survival (CSS), and disease-free survival (DFS) at 5-year follow-up were recorded and calculated.

Global drainage patterns and the origins of topographic relief on Earth, Mars, and Titan.

Rivers have eroded the topography of Mars, Titan, and Earth, creating diverse landscapes. However, the dominant processes that generated topography on Titan (and to some extent on early Mars) are not well known. We analyzed drainage patterns on all three bodies and found that large drainages, which record interactions between deformation and erosional modification, conform much better to long-wavelength topography on Titan and Mars than on Earth.

Rectal cancers with microscopic circumferential resection margin involvement (R1 resections): Survivals, patterns of recurrence, and prognostic factors.

Background And Objectives: We have reviewed our series of rectal cancer patients with circumferential resection margin involvement (R1) with particular regard to survival and prognostic factors.

Methods: R1 rectal cancer patients undergoing surgery at the Leicester Royal Infirmary between 1998 and 2008. Age, gender, radiological, and pathological tumor characteristics, neoadjuvant and adjuvant therapies were examined as prognostic factors on the overall survival (OS) and disease-free survival (DFS) at 5-year follow-up.

Circumferential resection margins and perineal complications after neoadjuvant long-course chemoradiotherapy followed by extralevator abdominoperineal excision of the rectum: Five years of activity at a single institution.

Background: Prone extralevator abdominoperineal excision of the rectum (ELAPE) has been introduced to improve the circumferential resection margins (CRM) compared with traditional APER.

Objective: We present short-term results achieved with prone ELAPE preceded by neoadjuvant chemoradiotherapy during the last 5 years of activity.

Design: A retrospective review was conducted.

Complete radiotherapy response in rectal cancer: A review of the evidence.

Complete response to chemoradiotherapy for rectal cancer is becoming a common clinical entity. Techniques to diagnose complete response and how to survey these patients without operative intervention are still unclear. We review the most recent evidence.

Is the routine use of a water-soluble contrast enema prior to closure of a loop ileostomy necessary? A review of a single institution experience.

Background: The aims of the study were to determine the radiological leak rate in those patients who had undergone a resection for left-sided colorectal cancer and to see if the presence of a leak can be related with the postoperative clinical period. We also aimed to identify any common factors between patients with leak.

Methods: A retrospective analysis of prospectively collected data of all patients who underwent a left-sided colorectal cancer resection with formation of a defunctioning ileostomy was undertaken.

Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice.

Resveratrol is widely promoted as a potential cancer chemopreventive agent, but a lack of information on the optimal dose prohibits rationally designed trials to assess efficacy. To challenge the assumption that "more is better," we compared the pharmacokinetics and activity of a dietary dose with an intake 200 times higher. The dose-response relationship for concentrations generated and the metabolite profile of [(14)C]-resveratrol in colorectal tissue of cancer patients helped us to define clinically achievable levels.

Straight to flexible sigmoidoscopy: rationalization of 2-week wait referrals in suspected colorectal cancer.

Aim: The 2-week wait pathway was designed to decrease the time from presentation to primary care of patients with 'red flag' symptoms of suspected cancer for review by a specialist for the diagnosis or exclusion of cancer. In our tertiary referral centre we have found that 968 colonoscopies per year are required to satisfy the demand for the 2-week wait, leading to limited colonoscopy availability for other services. We sought to determine the yield of colorectal cancer found at colonoscopy referred via the 2-week wait and referenced to the original red flag symptoms.

A modular gene targeting system for sequential transgene stacking in plants.

A modular, selection-based method was developed for site-specific integration of transgenes into a genomic locus to create multigene stacks. High-frequency gene targeting was obtained using zinc finger nuclease (ZFN)-mediated double-strand break (DSB) formation at a pre-defined target genomic location using a unique intron directly downstream of a promoter driving a selectable marker gene to facilitate homology between target and donor sequences. In this system, only insertion into the target locus leads to a functional selectable marker, and regeneration from random insertions of the promoterless donor construct are reduced on selection media.

Cancers of the anal canal: diagnosis, treatment and future strategies.

Anal cancer is an uncommon cancer; however, it is rising in incidence. There is confusion regarding nomenclature and the distinction between anal canal cancer and anal margin cancer. This article discusses the modern definition, etiology and staging of anal canal and anal margin cancers.

Together but apart: Caring for a spouse with dementia resident in a care facility.

This longitudinal, exploratory study was designed to better understand the lived experience of spousal caregivers age 60 and older providing care to partners with Alzheimer's disease and related dementias resident in a care facility. Twenty eight spousal caregivers were interviewed up to three times over a period of 2 years, and long-term care facility staff from four locations across British Columbia (BC), Canada participated in four focus groups. Thematic analysis of interview and focus group transcripts revealed a central, unifying theme 'together but apart'.

The gravity field and interior structure of Enceladus.

The small and active Saturnian moon Enceladus is one of the primary targets of the Cassini mission. We determined the quadrupole gravity field of Enceladus and its hemispherical asymmetry using Doppler data from three spacecraft flybys. Our results indicate the presence of a negative mass anomaly in the south-polar region, largely compensated by a positive subsurface anomaly compatible with the presence of a regional subsurface sea at depths of 30 to 40 kilometers and extending up to south latitudes of about 50°.

A rigid and weathered ice shell on Titan.

Several lines of evidence suggest that Saturn's largest moon, Titan, has a global subsurface ocean beneath an outer ice shell 50 to 200 kilometres thick. If convection is occurring, the rigid portion of the shell is expected to be thin; similarly, a weak, isostatically compensated shell has been proposed to explain the observed topography. Here we report a strong inverse correlation between gravity and topography at long wavelengths that are not dominated by tides and rotation.

The role of gender in housing for individuals with severe mental illness: a qualitative study of the Canadian service context.

Objective: This study was undertaken to examine the role of gender as it relates to access to housing among individuals with severe mental illness (SMI) in Canada.

Design: An exploratory, qualitative approach was used to assess the perspectives of Canadian housing experts. The focus of inquiry was on the role of gender and associated intersections (eg, ethnicity) in pathways to housing access and housing needs for individuals with SMI.

Teaching digital rectal examination to medical students using a structured workshop-a point in the right direction?

Background: Digital rectal examination (DRE) is an important skill in the investigation of rectal symptoms. This frequently performed examination is poorly taught and while students agree it is an important skill, their experience is often limited. Studies have suggested that structured teaching can improve confidence, knowledge, and ability of DRE.

Prolonged biologically active colonic tissue levels of curcumin achieved after oral administration--a clinical pilot study including assessment of patient acceptability.

Curcumin, the main constituent of turmeric, is suspected to possess cancer chemopreventive properties. Pharmacokinetic and pharmacodynamic parameters have been reported, but few data exist describing whether methodologies are suitably robust for curcuminoid detection in colonic biopsy specimens. Information on the acceptability of prolonged administration of daily curcumin is not available.

Psychogeriatric care: building rural community capacity.

Introduction: Since the late 1980s, British Columbia (BC) Canada has been undergoing a process of regionalization of health services which includes decentralization and the demand for self-sufficiency with respect to caring for people with mental health issues. In BC, regionalization has meant the continued downsizing of its one large provincial psychiatric hospital Riverview, which has resulted in relocating patients from this hospital to cities and towns throughout BC, and the establishment and/or renovation of psychiatric tertiary-care facilities to treat local community members who experience mental ill health. In the context of the relocation of psychiatric tertiary care, communities in northern BC face the specific challenge of having to provide these specialized services in remote settings, not only for people transferred from Riverview, but also for the increasing number of people 'aging-in-place' in a region that has the fastest growth of older adults in BC.