Carbon quantum dots (CQDs) are a versatile class of carbon-based nanomaterial frameworks that have previously been used as a diagnostic device, in sensing for environmental applications, in bioimaging, and for drug delivery systems. Their versatility stems from their ability to be chemically tailored functionalization to optimize properties for specific applications. In this study, we have synthesized lactic acid-derived nitrogen doped carbon quantum dots (LAdN-CQDs) and examined their ability to intervene in the conversion of soluble, monomeric hen egg-white lysozyme (HEWL) into mature fibrils.
View Article and Find Full Text PDFGraphene-based nanomaterials (graphene, graphene oxide, reduced graphene oxide, graphene quantum dots, graphene-based nanocomposites, etc.) are emerging as an extremely important class of nanomaterials primarily because of their unique and advantageous physical, chemical, biological, and optoelectronic aspects. These features have resulted in uses across diverse areas of scientific research.
View Article and Find Full Text PDFCarbon dots (CDs) are carbon nano materials (CNMs) that find use across several biological applications because of their water solubility, biocompatible nature, eco-friendliness, and ease of synthesis. Additionally, their physiochemical properties can be chemically tuned for further optimization towards specific applications. Here, we investigate the efficacy of C70-derived Graphene Acid Quantum Dots (GAQDs) in mitigating the transformation of soluble, monomeric Hen Egg-White Lysozyme (HEWL) to mature fibrils during its amyloidogenic trajectory.
View Article and Find Full Text PDFNitrated polycyclic aromatic hydrocarbons (nitro-PAHs) are persistent pollutants that have been introduced into the environment as a result of human activities. They are produced when PAHs undergo oxidation and are highly resistant to degradation, resulting in prolonged exposure and significant health risks for wildlife and humans. Nitro-PAHs' potential to induce cancer and mutations has raised concerns about their harmful effects.
View Article and Find Full Text PDFACS Appl Bio Mater
August 2024
Disorders of the central nervous system (CNS) which include a wide range of neurodegenerative and neurological conditions have become a serious global issue. The presence of CNS barriers poses a significant challenge to the progress of designing effective therapeutic delivery systems, limiting the effectiveness of drugs, genes, and other therapeutic agents. Natural nanocarriers present in biological systems have inspired researchers to design unique delivery systems through biomimicry.
View Article and Find Full Text PDFSediment contamination jeopardizes wetlands by harming aquatic organisms, disrupting food webs, and reducing biodiversity. Carcinogenic substances like heavy metals bioaccumulate in sediments and expose consumers to a greater risk of cancer. This study reports Pb, Cr, Cu, and Zn levels in sediments from eight wetlands in India.
View Article and Find Full Text PDFEnvironmental agents such as pesticides, weedicides and herbicides (collectively referred to as pesticides) are associated with the onset and pathogenesis of neurodegenerative disorders such as Parkinson's (PD) and Alzheimer's (AD) diseases. The development of blood-brain barrier (BBB)-penetrating therapeutic candidates to both prevent and treat the aforementioned xenotoxicant-induced neurodegenerative disorders remains an unmet need. Here, we examine whether caffeic-acid based Carbon Quantum Dots (CACQDs) can intervene in pesticide-associated onset and progress of the PD phenotype.
View Article and Find Full Text PDFMetals are micropollutants that cannot be degraded by microorganisms and are infiltrated into various environmental media, including both freshwater and marine water. Metals from polluted water are absorbed by many aquatic species, especially fish. Fish is a staple food in the diets of many regions in the world; hence, both the type and concentration of metals accumulated and transferred from contaminated water sources to fish must be determined and assessed.
View Article and Find Full Text PDFMetal-organic frameworks (MOFs) are amongst the most attractive porous polymeric networks with appealing properties. However, their inherent fragility, powder nature, low processibility, and handling present some exceptional challenges for high-tech commercial applications. Currently, economic and environmental concerns drive the development of some bioinspired polymeric matrices containing MOFs.
View Article and Find Full Text PDFGlobal water scarcity is exacerbated by climate change, population growth, and water pollution. Over half of the world's population will be affected by water shortages for at least a month annually by 2050 due toa lack of clean water sources. Even though recycling wastewater helps meet the growing demand, new pollutants, including pharmaceuticals and personal care products (PPCPs), pose a health threat since conventional methods cannot remove them and their environmental monitoring regulations are yet in place.
View Article and Find Full Text PDFA consortium of two biosurfactant-producing bacteria (Bacillus pumilus KS2 and Bacillus cereus R2) was developed to remediate petroleum hydrocarbon-contaminated paddy soil. Soil samples from a heavily contaminated rice field near Assam's Lakwa oilfield were collected and placed in earthen pots for treatment. After each month of incubation, 50 g of soil from each earthen pot was collected, and the soil TPH (ppm) in each sample was determined.
View Article and Find Full Text PDFAntibiotic Resistant Genes (ARGs) are an emerging environmental health threat due to the potential change in the human microbiome and selection for the emergence of antibiotic resistant bacteria. The rise of antibiotic resistant bacteria has caused a global health burden. The WHO (world health organization) predicts a rise in deaths due to antibiotic resistant infections.
View Article and Find Full Text PDFEmerging micro-pollutants have rapidly contaminated the agro-ecosystem, posing serious challenges to a sustainable future. The vast majority of them have infiltrated the soil and damaged agricultural fields and crops after being released from industry. These pollutants and their transformed products are also transported in vast quantities which further exacerbate the damage.
View Article and Find Full Text PDFNanotechnology has a wide range of agricultural applications, with emphasize on the development of novel nano-agrochemicals such as, nano-fertilizer and nano-pesticides. It has a significant impact on sustainable agriculture by increasing agricultural productivity, while reducing the use of inorganic fertilizers, pesticides, and herbicides. Nano-coating delivery methods for agrochemicals have improved agrochemical effectiveness, safety, and consistency.
View Article and Find Full Text PDFToxic and hazardous waste poses a serious threat to human health and the environment. Green remediation technologies are required to manage such waste materials, which is a demanding and difficult task. Here, effort was made to explore the role of Pseudomonas aeruginosa SR17 in alleviating naphthalene via catabolism and simultaneously producing biosurfactant.
View Article and Find Full Text PDFPlastic trash dumped into water bodies degrade over time into small fragments. These plastic fragments, which come under the category of micro-plastics (MPs), are generally 0.05-5 mm in size, and due to their small size they are frequently consumed by aquatic organisms.
View Article and Find Full Text PDFCurr Res Microb Sci
December 2021
Microbial fuel cells (MFCs) that generate bioelectricity from biodegradable waste have received considerable attention from biologists. Fungi play a significant role as both anodic and cathodic catalysts in MFCs. is a fungus with an ability to transfer electrons through mediators such as methylene blue (MB), neutral red (NR) or even without a mediator.
View Article and Find Full Text PDFIn developing countries, the use of antibiotics has helped to reduce the mortality rate by minimizing the deaths caused by pathogenic infections, but the costs of antibiotic contamination remain a major concern. Antibiotics are released into the environment, creating a complicated environmental problem. Antibiotics are used in human, livestock and agriculture, contributing to its escalation in the environment.
View Article and Find Full Text PDFA native strain of Bacillus paramycoides isolated from the leachate of coal mine overburden rocks was investigated for its potential to produce selenium nanoparticles (SeNPs) by biogenic reduction of selenite, one of the most toxic forms of selenium. 16S rDNA sequencing was used to identify the bacterial strain (SP3). The SeNPs were characterized using spectroscopic (UV-Vis absorbance, dynamic light scattering, X-ray diffraction, and Raman), surface charge measurement (zeta potential), and ultramicroscopic (FESEM, EDX, FETEM) analyses.
View Article and Find Full Text PDFThis review discusses the techniques available for detecting and inactivating of pathogens in municipal wastewater, landfill leachate, and solid waste. In view of the current COVID-19 pandemic, SARS-CoV-2 is being given special attention, with a thorough examination of all possible transmission pathways linked to the selected waste matrices. Despite the lack of works focused on landfill leachate, a systematic review method, based on cluster analysis, allows to analyze the available papers devoted to sewage sludge and wastewater, allowing to focalize the work on technologies able to detect and treat pathogens.
View Article and Find Full Text PDFRapid and drastic changes in the global climate today have given a strong impetus to developing newer climate-resilient phytoremediation approaches. These methods are of great public and scientific importance given the urgency of this environmental crisis. Climate change has adverse effects on the growth, outputs, phenology, and overall productivity of plants.
View Article and Find Full Text PDFBull Environ Contam Toxicol
March 2022
Halogenated compounds are one of the largest groups of environmental-hazardous chemicals. The removal of the halogen atom from the substrate is possible by the catalytic activity of a type of enzyme called dehalogenase. Hydrolytic dehalogenases are suggested to be a good biodegradation catalyst for halogenated compounds with potential bioremediation applications.
View Article and Find Full Text PDFThe study has been carried out to develop a plant-microbes assisted remediation technology to accelerate polyaromatic hydrocarbons (PAHs) degradation and heavy metals (HMs) removal in a microcosmic experiment. The quaternary mixture of PAHs (phenanthrene, anthracene, pyrene, and benzo[a] pyrene) and metals (Cr, Ni, and Pb) spiked the soil, constructing a microcosm; the microcosms were bioaugmented with newly developed plant bacterial consortia (Cpm and Cpm). The microcosms were amended with biochar (sieved particle size 0.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
June 2018
There are eight bisphenol analogues being identified and characterized; among them, bisphenol A (BPA) is on the priority list on the basis of its higher level of uses, occurrence, and toxicity. The endocrine system interfered by BPA has been inventoried as it has the same function as the natural hormone 17β-estradiol and binds mainly to the estrogen receptor (ER) to exhibit estrogenic activities. The BPA concentration in surface waters (14-1390 ng/L) in many parts of the world, such as Japan, Korea, China, and India, was also a significant concern.
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