Introduction: Oral squamous cell carcinoma (OSCC) is an aggressive and recurrent malignancy. Identification of unique and overexpressed cell surface antigens is important in the diagnosis and development of cancer vaccines and various therapies for OSCC. We have used real-time polymerase chain reaction (RT-PCR) for the expression of cell surface protein CD24 in both tissue samples and in blood samples to study the clinicopathological features as well as to determine the gene expression profile of CD24 in OSCC and explore its role as a potential target of clinical therapy.
View Article and Find Full Text PDFA 20-year-old male patient presented with a retruded chin and crowding of the upper front tooth region. The patient's problem list included skeletal class II malocclusion, retruded chin, and shallow mentolabial sulcus. A treatment plan was curated using clinical examination, cephalometric analysis, and 3D measurements, which included the advancement genioplasty of 5 mm.
View Article and Find Full Text PDFRecurrent bleeding due to mild trauma, tongue biting, poor oral hygiene, and expansion of the lesions causing difficulty in chewing, swallowing, or speaking is common sequelae of vascular lesions of the tongue. Cryosurgery is a technique for destroying lesions by the rapid freezing method. The necrotic tissue that results is allowed to slough naturally after the lesion is frozen.
View Article and Find Full Text PDFObjective: The purpose of this study was to eliminate orthodontic treatment in mild to moderate cases of condylar hyperplasia in its early stages by condylectomy.
Patients And Methods: A total of five patients (two females and three males) aged between 17 and 40 years were treated with unilateral condylectomy of the involved side without orthodontic treatment. All patients underwent standardized clinical and radiological examination at initial consultation, before surgery, immediately after surgery, and follow-up.