Factors affecting timing of hypothyroidism following radioactive iodine therapy (RAIT) for patients with Graves' disease: A 12-month observational study.

Background: This retrospective study analyzed factors influencing hypothyroidism development after radioactive iodine therapy for Graves' disease.

Patients And Methods: Three hundred and three patients with Graves' disease treated with radioactive iodine (RAI) from 2013 to 2022 at two Egyptian hospitals were included. Data collected included demographics, lab values, thyroid imaging, RAI doses, and outcomes.

Volumetric parameters of the primary tumor and whole-body tumor burden derived from baseline F-FDG PET/CT can predict overall survival in non-small cell lung cancer patients: initial results from a single institution.

Background: Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) are volumetric parameters derived from F-FDG PET/CT, suggested to have a prognostic value in cancer patients. Our study aimed to test whether these volumetric parameters of the primary tumor and whole-body tumor burden (WBTB) can predict overall survival (OS) in non-small cell lung cancer (NSCLC) patients.

Materials And Methods: Thirty biopsy-proven NSCLC patients who had not begun anti-tumor therapy were included in this prospective study.

Nanostructured Lipid Carriers to Mediate Brain Delivery of Temazepam: Design and In Vivo Study.

The opposing effect of the blood-brain barrier against the delivery of most drugs warrants the need for an efficient brain targeted drug delivery system for the successful management of neurological disorders. Temazepam-loaded nanostructured lipid carriers (NLCs) have shown possibilities for enhancing bioavailability and brain targeting affinity after oral administration. This study aimed to investigate these properties for insomnia treatment.