Publications by authors named "Hemasree Kommalapati"

Synopsis of recent research by authors named "Hemasree Kommalapati"

  • - Hemasree Kommalapati's recent research primarily focuses on the analysis and characterization of degradation impurities in ubrogepant, a medication used for treating migraines in adults, utilizing advanced analytical techniques.
  • - The study employs liquid chromatography-high resolution mass spectrometry (LC-HRMS) and nuclear magnetic resonance spectroscopy (NMR) to systematically identify and characterize these impurities, adhering to International Council for Harmonisation (ICH) guidelines.
  • - Additionally, the research incorporates in silico approaches to predict the degradation and toxicity of ubrogepant, providing a comprehensive understanding of the drug's stability and safety profile.