Publications by authors named "Hemasree Kommalapati"
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Synopsis of recent research by authors named "Hemasree Kommalapati"
- Hemasree Kommalapati's recent research primarily focuses on the analysis and characterization of degradation impurities in ubrogepant, a medication used for treating migraines in adults, utilizing advanced analytical techniques.
- The study employs liquid chromatography-high resolution mass spectrometry (LC-HRMS) and nuclear magnetic resonance spectroscopy (NMR) to systematically identify and characterize these impurities, adhering to International Council for Harmonisation (ICH) guidelines.
- Additionally, the research incorporates in silico approaches to predict the degradation and toxicity of ubrogepant, providing a comprehensive understanding of the drug's stability and safety profile.