Publications by authors named "Hemant Dhongade"

Objective: , which belongs to the family, is a popular garden plant that is widely used for the treatment of various diseases, such as urinary lithiasis, fever, hepatitis, cancer and jaundice. The objective of the present work was to investigate the antioxidant free-radical scavenging and the anticancer activities of against human breast-cancer cell lines.

Methods: The antioxidant activity of aqueous extract (OPAE) was investigated using different models, such as the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and the 2, 2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) models, as were the Fe chelation, the hydroxyl radical and superoxide radical scavenging, and total reducing power activities.

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. or is one of the most important plant widely cultivated in India. It belongs to family Moringaceae.

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Objectives: The current investigation was carried out to determine the cytotoxic and the antimicrobial activities of methanolic extracts of .

Methods: The stems, leaves, and whole plants were air dried and extracted with methanol by using a Soxhlet extractor for 72 hours at 55 - 60°C. The antimicrobial activities were determined from the zones of inhibition, which were measured by using the agar well diffusion method, and the cytotoxicity assays were performed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay method.

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The effect of Ca ion cross-linker on acryalamide grafted carboxymethyl xanthan gum (CMXG-g-PAAm) on the drug release was investigated. Previously, CMXG was synthesized from XG and further grafted to CMXG-g-PAAm to retard the drug release. Once the CaCl solution is added to CMXG-g-PAAm, Ca considerably affected the drug release mechanism mainly by diffusion and erosion.

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In the present work, an unreported graft copolymer of carboxymethyl xanthan gum and acrylamide has been synthesised by free radical polymerisation in a nitrogen atmosphere using ammonium persulphate as an initiator. The optimum reaction conditions adopted for affording maximum percentage of grafting including its grafting efficiency were obtained by varying the concentration of carboxymethyl xanthan gum from 4 to 24 g dm(-3); ammonium persulphate from 5×10(-4) to 30×10(-4)mol dm(-3); acrylamide from 0.4 to 1.

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