Publications by authors named "Hemaila Tariq"
Background: : Infertility is a global problem that brings about serious sexual and social consequences that strain the health sector and society. The expansion of CAG and GGC repeats in androgen receptor (AR) gene (Ensembl number ENSG00000169083) may lead to reduced fertility. Our objective was to determine the association of CAG and GGC repeats with altered sperm parameters in male infertile subjects.
View Article and Find Full Text PDFBackground In clinical settings, direct observation (DO) with feedback is an effective method to assess and improve learner performance. One tool used for DO is the mini-clinical evaluation exercise (Mini-CEX). We conducted a study to assess the effectiveness and feasibility of Mini-CEX for medical students at Aga Khan University, Karachi.
View Article and Find Full Text PDFObjective: To study the impact of vitamin B12, folic acid (FA) and methylmalonic acid (MMA) on sperm parameters; count, motility and morphology leading to male fertility.
Methods: The cross-sectional study comprised of one hundred and eighty-six subjects with normal sperm parameters (fertile) and 88 subjects with abnormal sperm parameters labelled as "infertile" from a sample population of Karachi, Pakistan. Vitamin B12, FA and MMA levels in serum were analysed by enzyme linked immune sorbent assay.
Article Synopsis
- - Infertility affects individuals globally, causing significant social and health challenges, with this study focusing on the impact of CAG and GGC repeats in the androgen receptor gene on male fertility.
- - Conducted at Aga Khan University in Pakistan, the study involved 376 males divided into two groups based on their sperm parameters, using PCR and statistical analysis to measure the gene repeats.
- - Results showed that longer CAG repeats were linked to more severe sperm issues, suggesting that genetic factors may contribute to male subfertility.
Objective: To compare stress markers and antioxidants in fertile and infertile males, and to explore their effects on reproductive hormones and fertility.
Methods: The cross-sectional case-control study was conducted from July 2017 to July 2018 at the Islamabad Clinic Serving Infertile Couples, Islamabad, Pakistan, and comprised male subjects aged 25-55 years. Infertile subjects were the cases, while healthy fertile males acted as the controls.