Synergistic Polymer-Surfactant-Complex Mediated Colloidal Interactions and Deposition.

Total internal reflection microscopy (TIRM) is used to directly, sensitively, and simultaneously measure colloidal interactions, dynamics, and deposition for a broad range of polymer-surfactant compositions. A deposition state diagram containing comprehensive information about particle interactions, trajectories, and deposition behavior is obtained for polymer-surfactant compositions covering four decades in both polymer and surfactant concentrations. Bulk polymer-surfactant phase behavior and surface properties are characterized to provide additional information to interpret mechanisms.

Altering the edge chemistry of bicelles with peptoids.

Cell function is tied to the interactions that occur within and across the cell membrane. Therefore, understanding membrane-affiliated interactions is important to many biomedical applications. Advancing the body of knowledge about these interactions will lead to discoveries in biomarker detection and therapeutic targets for disease detection and treatment.