Publications by authors named "Heloisa S Sanchuki"
Article Synopsis
- The carbohydrate-uptake phosphorelay system (PTS) in bacteria, particularly E. coli, plays a role in regulating the use of secondary carbon sources, although the nitrogen-related version of PTS does not directly influence nitrogen metabolism as previously thought.
- Research indicated that deleting the ptsN gene in E. coli leads to impaired growth in minimal media, highlighting its importance for bacterial fitness.
- Proteomic analysis revealed that ptsN does not affect the canonical nitrogen regulatory system but is essential for balancing the activities of sigma factors RpoS and RpoD, causing a shift towards increased expression of RpoS-dependent genes when ptsN is absent.
