Sputtered crystalline TiO film drives improved surface properties of titanium-based biomedical implants.

Different crystalline phases in sputtered TiO films were tailored to determine their surface and electrochemical properties, protein adsorption and apatite layer formation on titanium-based implant material. Deposition conditions of two TiO crystalline phases (anatase and rutile) were established and then grown on commercially pure titanium (cpTi) by magnetron sputtering to obtain the following groups: A-TiO (anatase), M-TiO (anatase and rutile mixture), R-TiO (rutile). Non-treated commercially pure titanium (cpTi) was used as a control.

Outlining cell interaction and inflammatory cytokines on UV-photofunctionalized mixed-phase TiO thin film.

Photofunctionalization mediated by ultraviolet (UV) light seems to be a promising approach to improve the physico-chemical characteristics and the biological response of titanium (Ti) dental implants. Seeing that photofunctionalization is able to remove carbon from the surface, besides to promote reactions on the titanium dioxide (TiO) layer, coating the Ti with a stable TiO film could potentialize the UV effect. Thus, here we determined the impact of UV-photofunctionalized mixed-phase (anatase and rutile) TiO films on the physico-chemical properties of Ti substrate and cell biology.

Proteome analysis of the salivary pellicle formed on titanium alloys containing niobium and zirconium.

The chemical composition of biomaterials can drive their biological responses; therefore, this in vitro study aimed to evaluate the proteomic profile of the salivary pellicle formed on titanium (Ti) alloys containing niobium (Nb) and zirconium (Zr). The experimental groups consisted of Ti35NbxZr (x = 5 and 10 wt%) alloys, and commercially pure titanium (cpTi); titanium aluminium vanadium (Ti6Al4V) alloys were used as controls. The physical and chemical characteristics of the Ti materials were analysed.

Antibacterial photocatalytic activity of different crystalline TiO phases in oral multispecies biofilm.

Objective: Titanium dioxide (TiO) incorporation in biomaterials is a promising technology due to its photocatalytic and antibacterial activities. However, the antibacterial potential of different TiO crystalline structures on a multispecies oral biofilm remains unknown. We hypothesized that the different crystalline TiO phases present different photocatalytic and antibacterial activities.