Does Intraoperative Extracochlear Electrocochleography Correlate With Postoperative Audiometric Hearing Thresholds in Cochlear Implant Surgery? A Retrospective Analysis of Cochlear Monitoring.

In recent years, tools for early detection of irreversible trauma to the basilar membrane during hearing preservation cochlear implant (CI) surgery were established in several clinics. A link with the degree of postoperative hearing preservation in patients was investigated, but patient populations were usually small. Therefore, this study's aim was to analyze data from intraoperative extracochlear electrocochleography (ECochG) recordings for a larger group.

Intratympanic application of triamcinolone in sudden hearing loss-radiologic anatomy in cone beam CT and its' correlation to clinical outcome.

Purpose: To evaluate temporal bone cone-beam CT in patients with idiopathic sudden sensorineural hearing loss (ISSNHL) being treated with primary and secondary intratympanic (IT) triamcinolone and to possibly correlate these results to the clinical outcome.

Methods: Retrospective analysis of patients treated with IT triamcinolone for ISSNHL at our department in 2018. Pre- and post-therapeutic audiologic examinations included four-tone average (FTA) at 0.

Monitoring of the Inner Ear Function During and After Cochlear Implant Insertion Using Electrocochleography.

To preserve residual hearing during cochlear implant (CI) surgery, it is desirable to use intraoperative monitoring of inner ear function (cochlear monitoring), especially during electrode insertion. A promising method is electrocochleography (ECochG). Within this project, the relations between ongoing responses (ORs), recorded extra- and intracochlearly (EC and IC), and preservation of residual hearing were investigated.

Cochlear implantation in children with meningitis related deafness: The influence of electrode impedance and implant charge on auditory performance - A case control study.

Objectives: Bacterial meningitis can cause a labyrinthitis. Consequences often are intracochlear soft tissue neoformation (cochlear obliteration) or intracochlear osteoneogenesis (cochlear ossification) and deafness. Cochlear implantation becomes challenging and hearing rehabilitation is complicated.

The Summating Potential Is a Reliable Marker of Electrode Position in Electrocochleography: Cochlear Implant as a Theragnostic Probe.

Objective: For the increasing number of cochlear implantations in subjects with residual hearing, hearing preservation, and thus the prevention of implantation trauma, is crucial. A method for monitoring the intracochlear position of a cochlear implant (CI) and early indication of imminent cochlear trauma would help to assist the surgeon to achieve this goal. The aim of this study was to evaluate the reliability of the different electric components recorded by an intracochlear electrocochleography (ECochG) as markers for the cochleotopic position of a CI.

Radiologic detectability of the cochlear implant electrode fixation clip using cone beam computed tomography.

Introduction: With the aim of preventing migration of cochlear implantation electrodes in the postoperative course, an electrode fixation clip has been developed. It is characterized by two clips of double U-geometry. The bone fixation clip will be clamped on the bony incus bridge, and the electrode fixation clip is clamped to the electrode lead.

High-frequency jet ventilation for endolaryngotracheal surgery--chart review and procedure analysis from the surgeon's and the anaesthesiologist's point of view.

Objective: High-frequency jet ventilation (HFJV) arose as a ventilation alternative in laryngotracheal surgery as it offers the surgeon a better overview and more space for microsurgical manipulations. On the contrary, anaesthesiologic monitoring is limited and (relative) contraindications exist. The aim of this study was to evaluate the procedure.

[Group phenomena in medical decisions--an analysis among residents of a department of otolaryngology].

Objective: Group phenomena concern the behaviour of particular groups which differs from that of individuals. One relevant phenomenon is the 'risky shift', which describes the observation of groups making riskier decisions than individuals. These phenomena have not been investigated for German physicians as yet.

[High-frequency jet ventilation in otorhinolaryngology - surgical and anaesthesiologic issues].

Background: High-frequency jet ventilation (HFJV) through thin catheters creates more room for surgical procedures in laryngotracheal surgery, while few contraindications exist. In contrast, the anaesthesiologist has to cope with reduced monitoring and numerous contraindications. Therefore, every participating discipline has to thoroughly know the method.

Tolerability of sialendoscopy under local anesthesia.

Objectives: We sought to investigate patients' tolerance of sialendoscopy of the parotid and submandibular glands with local anesthesia.

Methods: In a retrospective case series of 84 adult patients who underwent sialendoscopy with local anesthesia at an academic tertiary referral hospital, we analyzed patients' demographic data, American Society of Anesthesiologists (ASA) status score, perioperative cardiovascular parameters, and results on a 2-question survey.

Results: Of the 84 patients, 44 were female and 40 were male (mean age, 48.

[Comparison of ready-to-use devices for emergency cricothyrotomy : randomized and controlled feasibility study on a mannequin].

Background: According to various algorithms of airway management, emergency cricothyrotomy (coniotomy) represents the ultimate step for managing the difficult airway. As most physicians have limited experience with this technique several ready-to-use devices have emerged on the market with the aim of simplifying the procedure. However, they differ in details, such as configuration or the order of particular steps.

Impact of partial mastoid obliteration on caloric vestibular function in canal wall down mastoidectomy.

Objective: To evaluate the influence of our technique of partial mastoid obliteration with autologous bone pâté covered by cartilage plates on vestibular stimulation.

Methods: Twenty-six patients who were treated for recurrent chronic otitis media by revision canal wall down tympanomastoidectomy and subsequent partial obliteration were invited for follow-up; 18 patients agreed to a complete follow-up including vestibular testing. Patients received questionnaires for evaluating preoperative and postoperative symptoms associated with vertigo.

Cartilage plate tympanoplasty.

Objectives: The purpose of this work was to report our modified cartilage plate tympanoplasty technique ("tulip leaves") and to analyze its clinical outcome in primary and recurrent cases of chronic otitis media with and without cholesteatoma.

Study Design: Clinical retrospective study.

Methods: Patients being operated on with this technique at the University Department of Otorhinolaryngology, Dresden, Germany, between 1993 and 2001 were invited for survey, otomicroscopy, and pure-tone audiometry in 2003.

Cervical hemorrhage due to spontaneous rupture of the superior thyroid artery: Case report and review of the literature.

Background: Beneath the different reasons for cervical masses, a spontaneous hemorrhage presents a rare and life-threatening condition.

Methods And Results: We present the rare case of a 62-year-old man who was presented with a dramatically enlarging cervical mass causing respiratory distress because of upper airway compression. An endotracheal intubation was lifesaving and avoided tracheotomy.

Carbon dioxide laser endoscopic diverticulotomy for Zenker's diverticulum: results and complications in a consecutive series of 40 patients.

Background: Numerous studies regarding CO2 laser endoscopic diverticulotomy for the treatment of Zenker's diverticulum exist. They show differences in complications, hospitalization time and postoperative treatment.

Objectives: We report our experiences and work out recommendations for postoperative care.

Safety and efficacy of botulinum toxin therapy in otorhinolaryngology: experience from 1,000 treatments.

Objectives: The objective of this study was to analyze the safety and efficacy of botulinum toxin (BTX) therapy in a series of 1,000 treatments on 261 consecutive patients at the University Department of Otorhinolaryngology-Head and Neck Surgery, Cologne, Germany.

Study Design/methods: A prospective computer database was analyzed, and all patient charts were reviewed retrospectively. In doing so, the main focus was put on patient characteristics, treatment methods, efficacy, unwanted side effects, and reinjection rate.

Estradiol, tamoxifen and ICI 182,780 alter alpha3 and beta1 integrin expression and laminin-1 adhesion in oral squamous cell carcinoma cell cultures.

Adhesion molecules such as integrins and extracellular matrix proteins like laminins have been identified to play an important role in cell proliferation, migration and invasion by regulating cell-extracellular matrix interaction in various cancers including oral squamous cell carcinoma (OSCC). In this study, the effect of estradiol (E2), and the E2 antagonists tamoxifen (TAM) and ICI 182,780 (ICI) on the expression of integrins and adhesion to laminin-1 in different OSCC in vitro models was analyzed. TAM and ICI inhibited growth in all OSCC cell lines.

[Multiple primary pleomorphic adenomas of the unilateral parotid gland].

Background: Classical lateral parotidectomy is the standard surgical procedure for the management of lateral lobe parotid pleomorphic adenomas in most clinical centres. Extracapsular dissection and subtotal lateral parotidectomy are alternatively discussed in current literature and preferred by many authors.

Case: We report on a 20-year-old patient with multiple primary pleomorphic adenomas in the unilateral parotid gland, which preoperatively presented as a solitary tumour node.

The influence of tamoxifen on growth behavior and cell-cell adhesion in OSCC in vitro.

The aim of this study was to evaluate the influence of tamoxifen on the growth and aggregation behavior, focusing on the expression pattern of E-cadherin and beta-catenin, in oral squamous cell carcinoma (OSCC) in vitro. Oral squamous cancer cell lines (UM-SCC-14A, UM-SCC-14B and UM-SCC-14C) were treated with various concentrations of tamoxifen. Growth and aggregation behavior as well as the protein expression and its changes were analysed.

Distinct immunohistochemical findings in columnar epithelium of esophageal inlet patch and of Barrett's esophagus.

Immunohistochemistry was performed on biopsies of columnar mucosa from 11 patients with Barrett's esophagus and 11 patients with columnar mucosa in the cranial esophagus, the "inlet patch." Both epithelia contained endocrine cells, immunoreactive to antisera against serotonin, glucagon, somatostatin, and pancreatic polypeptide; the specialized mucosa of Barrett's esophagus contained, in addition, neurotensin-immunoreactive cells, and in the mucosa of an inlet patch we found a gastrin cell. These findings are not compatible with some of the current theories on the origin of these epithelia.